TY - JOUR
T1 - Typing of 49 autosomal SNPs by SNaPshot in the Slovenian population
AU - Drobnic, Katja
AU - Børsting, Claus
AU - Rockenbauer, Eszter
AU - Tomas, Carmen
AU - Morling, Niels
N1 - Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
PY - 2010/10
Y1 - 2010/10
N2 - A total of 157 unrelated individuals residing in Slovenia were typed for 49 of the autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex with the SNaPshot® assay. We obtained full SNP profiles in all but one individual and perfect concordance was obtained in duplicated analyses. Allele frequencies are presented for the 49 SNPs. No deviation from HWE was observed for any SNP. FIS and FST were estimated. A principal coordinate analysis performed on six populations (Slovenian, Danish, Somali, Greenland, Turkish and Chinese) showed that the Slovenian population grouped with the Danish population. The mean power of discrimination for the Slovenian population was 1.1 × 10-19, and the mean exclusion probability for trios was 99.96%.
AB - A total of 157 unrelated individuals residing in Slovenia were typed for 49 of the autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex with the SNaPshot® assay. We obtained full SNP profiles in all but one individual and perfect concordance was obtained in duplicated analyses. Allele frequencies are presented for the 49 SNPs. No deviation from HWE was observed for any SNP. FIS and FST were estimated. A principal coordinate analysis performed on six populations (Slovenian, Danish, Somali, Greenland, Turkish and Chinese) showed that the Slovenian population grouped with the Danish population. The mean power of discrimination for the Slovenian population was 1.1 × 10-19, and the mean exclusion probability for trios was 99.96%.
U2 - 10.1016/j.fsigen.2010.01.014
DO - 10.1016/j.fsigen.2010.01.014
M3 - Journal article
C2 - 20457083
SN - 1872-4973
VL - 4
SP - e125-7
JO - Forensic Science International: Genetics
JF - Forensic Science International: Genetics
IS - 5
ER -