TY - JOUR
T1 - Towards fabrication of 3D printed medical devices to prevent biofilm formation.
AU - Sandler, Niklas
AU - Salmela, Ida
AU - Fallarero, Adyary
AU - Rosling, Ari
AU - Khajeheian, Mohammad
AU - Kolakovic, Ruzica
AU - Genina, Natalja
AU - Nyman, Johan
AU - Vuorela, Pia
PY - 2014/1/1
Y1 - 2014/1/1
N2 - The use of three-dimensional (3D) printing technologies is transforming the way that materials are turned into functional devices. We demonstrate in the current study the incorporation of anti-microbial nitrofurantoin in a polymer carrier material and subsequent 3D printing of a model structure, which resulted in an inhibition of biofilm colonization. The approach taken is very promising and can open up new avenues to manufacture functional medical devices in the future.
AB - The use of three-dimensional (3D) printing technologies is transforming the way that materials are turned into functional devices. We demonstrate in the current study the incorporation of anti-microbial nitrofurantoin in a polymer carrier material and subsequent 3D printing of a model structure, which resulted in an inhibition of biofilm colonization. The approach taken is very promising and can open up new avenues to manufacture functional medical devices in the future.
KW - Anti-Bacterial Agents
KW - Anti-Bacterial Agents: administration & dosage
KW - Anti-Bacterial Agents: chemistry
KW - Anti-Bacterial Agents: pharmacology
KW - Attachment Sites, Microbiological
KW - Attachment Sites, Microbiological: drug effects
KW - Biofilms
KW - Biofilms: drug effects
KW - Biofilms: growth & development
KW - Equipment Design
KW - Equipment and Supplies
KW - Health Care Sector
KW - Indicators and Reagents
KW - Microbial Sensitivity Tests
KW - Nitrofurantoin
KW - Nitrofurantoin: administration & dosage
KW - Nitrofurantoin: chemistry
KW - Nitrofurantoin: pharmacology
KW - Oxazines
KW - Oxazines: administration & dosage
KW - Oxazines: chemistry
KW - Printing
KW - Spectrophotometry, Ultraviolet
KW - Staphylococcus aureus
KW - Staphylococcus aureus: drug effects
KW - Xanthenes
KW - Xanthenes: administration & dosage
KW - Xanthenes: chemistry
U2 - 10.1016/j.ijpharm.2013.11.001
DO - 10.1016/j.ijpharm.2013.11.001
M3 - Journal article
C2 - 24239831
SN - 0378-5173
VL - 459
SP - 62
EP - 64
JO - International Journal of Pharmaceutics
JF - International Journal of Pharmaceutics
IS - 1-2
ER -