TY - JOUR
T1 - The liquid-ordered state comes of age
AU - Mouritsen, Ole G.
PY - 2010/7/1
Y1 - 2010/7/1
N2 - Biomembranes are unique states of soft matter that share some of their materials properties with the mesophases of liquid crystals. Although of genuinely fluid character, membranes can display ordered states under physiological conditions, and it appears that their lateral organization and the related functional properties are intimately coupled to states in-between order and disorder. Hence, the liquid-ordered state of membranes, which owes its existence to the unique ability of cholesterol to mediate between order and disorder, has moved center stage in the characterization of membranes in terms of domains or rafts.
AB - Biomembranes are unique states of soft matter that share some of their materials properties with the mesophases of liquid crystals. Although of genuinely fluid character, membranes can display ordered states under physiological conditions, and it appears that their lateral organization and the related functional properties are intimately coupled to states in-between order and disorder. Hence, the liquid-ordered state of membranes, which owes its existence to the unique ability of cholesterol to mediate between order and disorder, has moved center stage in the characterization of membranes in terms of domains or rafts.
KW - Cholesterol
KW - Lipid bilayer
KW - Lipid domains
KW - Liquid-ordered phase
UR - http://www.scopus.com/inward/record.url?scp=77954757145&partnerID=8YFLogxK
U2 - 10.1016/j.bbamem.2010.02.017
DO - 10.1016/j.bbamem.2010.02.017
M3 - Review
C2 - 20170626
AN - SCOPUS:77954757145
SN - 0005-2736
VL - 1798
SP - 1286
EP - 1288
JO - B B A - Biomembranes
JF - B B A - Biomembranes
IS - 7
ER -