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The GABAA Antagonist DPP-4-PIOL Selectively Antagonises Tonic over Phasic GABAergic Currents in Dentate Gyrus Granule Cells
Kim Boddum,
Bente Frølund
,
Uffe Kristiansen
7
Citationer (Scopus)
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Keyphrases
GABAA Receptor (GABAAR)
100%
GABAergic
100%
GABAA Antagonist
100%
3-isoxazolols
100%
Tonic
100%
Dentate Granule Cells
100%
Tonic Current
80%
IC50 Value
40%
Receptor Current
20%
Tonic Inhibition
20%
Extrasynaptic GABAA Receptors
20%
Pharmacological Profile
20%
Extrasynaptic
20%
Post-stroke
20%
Selective Inhibition
20%
GABA Release
20%
Antagonism
20%
Spontaneous Excitatory Postsynaptic Current (sEPSC)
20%
Pharmacology, Toxicology and Pharmaceutical Science
4 Aminobutyric Acid A Receptor Blocking Agent
100%
Bromide
100%
Receptor
100%
4 Aminobutyric Acid
66%
IC50
33%
Cerebrovascular Accident
16%
Neuroscience
GABAA Receptor
100%
Dentate Gyrus
100%
Granule Cell
100%
Gamma-Aminobutyric Acid
66%
Cerebrovascular Accident
16%