The epidermal growth factor precursor in the rat kidney seems to be processed by an aprotinin sensitive proteinase

Ebba Nexø, Steen Seier Poulsen, Lasse Raaberg

Abstract

Epidermal growth factor (EGF) is synthesized as a membrane bound precursor in the rat kidney. The precursor seems to be processed by an aprotinin sensitive proteinase. Intravenous infusion of aprotinin reduces the urinary excretion of EGF by 85% and increases the amount of renal EGF. Kidney membranes incubated at 37 degrees C release EGF and this release is inhibited by aprotinin.
OriginalsprogEngelsk
TidsskriftAgents and actions. Supplements
Vol/bind38 ( Pt 2)
Sider (fra-til)183-90
Antal sider8
ISSN0379-0363
StatusUdgivet - 1992

Fingeraftryk

Dyk ned i forskningsemnerne om 'The epidermal growth factor precursor in the rat kidney seems to be processed by an aprotinin sensitive proteinase'. Sammen danner de et unikt fingeraftryk.

Citationsformater