The congenital "ant-egg" cataract phenotype is caused by a missense mutation in connexin46

Lars Hansen, Wenliang Yao, Hans Eiberg, Mikkel Funding, Ruth Riise, Klaus Wilbrandt Kjær, James Fielding Hejtmancik, Thomas Rosenberg

36 Citationer (Scopus)

Abstract

"Ant-egg" cataract is a rare, distinct variety of congenital/infantile cataract that was reported in a large Danish family in 1967. This cataract phenotype is characterized by ant-egg-like bodies embedded in the lens in a laminar configuration and is inherited as an autosomal dominant trait. We retrieved the family and performed linkage analysis to determine the disease locus and identify the mutated gene.
OriginalsprogEngelsk
TidsskriftMolecular Vision
Vol/bind12
Udgave nummer116
Sider (fra-til)1033-1039
Antal sider7
ISSN1090-0535
StatusUdgivet - 2006

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