TY - JOUR
T1 - Systematic reviews of diagnostic test accuracy
AU - Leeflang, Mariska M G
AU - Deeks, Jonathan J
AU - Gatsonis, Constantine
AU - Bossuyt, Patrick M M
AU - Hilden, Jørgen
N1 - Keywords: Diagnostic Tests, Routine; Humans; Information Storage and Retrieval; Meta-Analysis as Topic; ROC Curve; Research Design; Review Literature as Topic; Sensitivity and Specificity
PY - 2008
Y1 - 2008
N2 - More and more systematic reviews of diagnostic test accuracy studies are being published, but they can be methodologically challenging. In this paper, the authors present some of the recent developments in the methodology for conducting systematic reviews of diagnostic test accuracy studies. Restrictive electronic search filters are discouraged, as is the use of summary quality scores. Methods for meta-analysis should take into account the paired nature of the estimates and their dependence on threshold. Authors of these reviews are advised to use the hierarchical summary receiver-operating characteristic or the bivariate model for the data analysis. Challenges that remain are the poor reporting of original diagnostic test accuracy studies and difficulties with the interpretation of the results of diagnostic test accuracy research.
AB - More and more systematic reviews of diagnostic test accuracy studies are being published, but they can be methodologically challenging. In this paper, the authors present some of the recent developments in the methodology for conducting systematic reviews of diagnostic test accuracy studies. Restrictive electronic search filters are discouraged, as is the use of summary quality scores. Methods for meta-analysis should take into account the paired nature of the estimates and their dependence on threshold. Authors of these reviews are advised to use the hierarchical summary receiver-operating characteristic or the bivariate model for the data analysis. Challenges that remain are the poor reporting of original diagnostic test accuracy studies and difficulties with the interpretation of the results of diagnostic test accuracy research.
M3 - Journal article
C2 - 19075208
SN - 0003-4819
VL - 149
SP - 889
EP - 897
JO - Annals of Internal Medicine
JF - Annals of Internal Medicine
IS - 12
ER -