Surveillance for Secure Differentiation

TY - JOUR

T1 - Surveillance for Secure Differentiation

AU - Hamilton, William B

AU - Brickman, Joshua M

N1 - Copyright © 2017 Elsevier Inc. All rights reserved.

PY - 2017/1/5

Y1 - 2017/1/5

N2 - The precise place and time where embryonic differentiation begins is regulated by regionalized signaling. In this issue of Cell Stem Cell, Wang et al. (2017) investigate how converging Wnt and Nodal signals promote mesendoderm through a p53, Wnt3 feed-forward loop, pointing to a mechanism by which cells gauge time and fitness during differentiation.

AB - The precise place and time where embryonic differentiation begins is regulated by regionalized signaling. In this issue of Cell Stem Cell, Wang et al. (2017) investigate how converging Wnt and Nodal signals promote mesendoderm through a p53, Wnt3 feed-forward loop, pointing to a mechanism by which cells gauge time and fitness during differentiation.

U2 - 10.1016/j.stem.2016.12.011

DO - 10.1016/j.stem.2016.12.011

M3 - Journal article

C2 - 28061352

SN - 1934-5909

VL - 20

SP - 3

EP - 5

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 1

ER -