Structural variations of staphylococcal cassette chromosome mec Type IVa in Staphylococcus aureus clonal complex 8 and unrelated lineages

Peter Panduro Damborg; Mette Damkjær Bartels; Kit Boye; Luca Guardabassi; Henrik T. Westh

doi:10.1128/AAC.00012-11

Structural variations of staphylococcal cassette chromosome mec Type IVa in Staphylococcus aureus clonal complex 8 and unrelated lineages

Peter Panduro Damborg, Mette Damkjær Bartels, Kit Boye, Luca Guardabassi, Henrik T. Westh

7 Citationer (Scopus)

Abstract

PCR mapping of staphylococcal cassette chromosome mec type IVa and adjacent mobile elements in 94 methicillin-resistant Staphylococcus aureus (MRSA) strains identified two primary structures (A and B) that could be further classified into two (A1 and A2) and five (B1 to B5) variants, primarily based on structural differences in the orfX-J3 region. While spa type t008 (USA300) invariably contained the A variants, other spa types belonging to clonal complex 8 and unrelated lineages generally contained B variants. These findings have important implications for the typing and identification of MRSA strains containing B variants.

Originalsprog	Engelsk
Tidsskrift	Antimicrobial Agents and Chemotherapy
Vol/bind	55
Udgave nummer	8
Sider (fra-til)	3932-3935
Antal sider	4
ISSN	0066-4804
DOI	https://doi.org/10.1128/AAC.00012-11
Status	Udgivet - aug. 2011

Adgang til dokumentet

10.1128/AAC.00012-11

Structural variations of staphylococcal cassette chromosome mec Type IVa in Staphylococcus aureus clonal complex 8 and unrelated lineagesForlagets udgivne version, 1,23 MB

Citationsformater

Structural variations of staphylococcal cassette chromosome mec Type IVa in Staphylococcus aureus clonal complex 8 and unrelated lineages. / Damborg, Peter Panduro; Bartels, Mette Damkjær; Boye, Kit et al.

I: Antimicrobial Agents and Chemotherapy, Bind 55, Nr. 8, 08.2011, s. 3932-3935.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

@article{8915f152c073458faf98a12fe46c9e2f,

title = "Structural variations of staphylococcal cassette chromosome mec Type IVa in Staphylococcus aureus clonal complex 8 and unrelated lineages",

abstract = "PCR mapping of staphylococcal cassette chromosome mec type IVa and adjacent mobile elements in 94 methicillin-resistant Staphylococcus aureus (MRSA) strains identified two primary structures (A and B) that could be further classified into two (A1 and A2) and five (B1 to B5) variants, primarily based on structural differences in the orfX-J3 region. While spa type t008 (USA300) invariably contained the A variants, other spa types belonging to clonal complex 8 and unrelated lineages generally contained B variants. These findings have important implications for the typing and identification of MRSA strains containing B variants.",

author = "Damborg, {Peter Panduro} and Bartels, {Mette Damkj{\ae}r} and Kit Boye and Luca Guardabassi and Westh, {Henrik T.}",

year = "2011",

month = aug,

doi = "10.1128/AAC.00012-11",

language = "English",

volume = "55",

pages = "3932--3935",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "8",

}

TY - JOUR

T1 - Structural variations of staphylococcal cassette chromosome mec Type IVa in Staphylococcus aureus clonal complex 8 and unrelated lineages

AU - Damborg, Peter Panduro

AU - Bartels, Mette Damkjær

AU - Boye, Kit

AU - Guardabassi, Luca

AU - Westh, Henrik T.

PY - 2011/8

Y1 - 2011/8

N2 - PCR mapping of staphylococcal cassette chromosome mec type IVa and adjacent mobile elements in 94 methicillin-resistant Staphylococcus aureus (MRSA) strains identified two primary structures (A and B) that could be further classified into two (A1 and A2) and five (B1 to B5) variants, primarily based on structural differences in the orfX-J3 region. While spa type t008 (USA300) invariably contained the A variants, other spa types belonging to clonal complex 8 and unrelated lineages generally contained B variants. These findings have important implications for the typing and identification of MRSA strains containing B variants.

AB - PCR mapping of staphylococcal cassette chromosome mec type IVa and adjacent mobile elements in 94 methicillin-resistant Staphylococcus aureus (MRSA) strains identified two primary structures (A and B) that could be further classified into two (A1 and A2) and five (B1 to B5) variants, primarily based on structural differences in the orfX-J3 region. While spa type t008 (USA300) invariably contained the A variants, other spa types belonging to clonal complex 8 and unrelated lineages generally contained B variants. These findings have important implications for the typing and identification of MRSA strains containing B variants.

U2 - 10.1128/AAC.00012-11

DO - 10.1128/AAC.00012-11

M3 - Journal article

C2 - 21646488

SN - 0066-4804

VL - 55

SP - 3932

EP - 3935

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 8

ER -

Structural variations of staphylococcal cassette chromosome mec Type IVa in Staphylococcus aureus clonal complex 8 and unrelated lineages

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater