Social gradient in allostatic load among Danish men and women in late midlife

Åse Marie Hansen; Rikke Lund; Helle Bruunsgaard Kemp; Naja Hulvej Rod; Anne Helene Garde; Drude Molbo; Kirsten Avlund

doi:10.1177/0898264313508187

Social gradient in allostatic load among Danish men and women in late midlife

Åse Marie Hansen, Rikke Lund, Helle Bruunsgaard Kemp, Naja Hulvej Rod, Anne Helene Garde, Drude Molbo, Kirsten Avlund

14 Citationer (Scopus)

Abstract

Objective: The objective of the present study is to describe the prevalence of allostatic load (AL) among Danish men and women in late midlife, and if there is a social gradient in AL. Method: A total of 5,420 participants from the Copenhagen Aging and Midlife Biobank (CAMB) aged 48 to 63 years (68.5% men, 31.5% women) underwent a health examination including standardized measures of height, weight, body fat, and blood pressure in 2009-2011. AL (range 0-14) was established by summing the scores of the poorest quartile for each of 14 biological variables related to the metabolic and immune systems. Results: We found a social gradient in AL in late midlife among men and women living in Denmark. Discussion: AL may be a potential biomarker for early aging in countries with a strong social welfare system. It is important for intervention studies to be aware of this type of biological vulnerability already present in late midlife.

Originalsprog	Engelsk
Tidsskrift	Journal of Aging and Health
Vol/bind	26
Udgave nummer	1
Sider (fra-til)	72-87
Antal sider	16
ISSN	0898-2643
DOI	https://doi.org/10.1177/0898264313508187
Status	Udgivet - feb. 2014

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10.1177/0898264313508187

Citationsformater

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abstract = "Objective: The objective of the present study is to describe the prevalence of allostatic load (AL) among Danish men and women in late midlife, and if there is a social gradient in AL. Method: A total of 5,420 participants from the Copenhagen Aging and Midlife Biobank (CAMB) aged 48 to 63 years (68.5% men, 31.5% women) underwent a health examination including standardized measures of height, weight, body fat, and blood pressure in 2009-2011. AL (range 0-14) was established by summing the scores of the poorest quartile for each of 14 biological variables related to the metabolic and immune systems. Results: We found a social gradient in AL in late midlife among men and women living in Denmark. Discussion: AL may be a potential biomarker for early aging in countries with a strong social welfare system. It is important for intervention studies to be aware of this type of biological vulnerability already present in late midlife.",

author = "Hansen, {{\AA}se Marie} and Rikke Lund and Kemp, {Helle Bruunsgaard} and Rod, {Naja Hulvej} and Garde, {Anne Helene} and Drude Molbo and Kirsten Avlund",

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doi = "10.1177/0898264313508187",

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T1 - Social gradient in allostatic load among Danish men and women in late midlife

AU - Hansen, Åse Marie

AU - Lund, Rikke

AU - Kemp, Helle Bruunsgaard

AU - Rod, Naja Hulvej

AU - Garde, Anne Helene

AU - Molbo, Drude

AU - Avlund, Kirsten

PY - 2014/2

Y1 - 2014/2

N2 - Objective: The objective of the present study is to describe the prevalence of allostatic load (AL) among Danish men and women in late midlife, and if there is a social gradient in AL. Method: A total of 5,420 participants from the Copenhagen Aging and Midlife Biobank (CAMB) aged 48 to 63 years (68.5% men, 31.5% women) underwent a health examination including standardized measures of height, weight, body fat, and blood pressure in 2009-2011. AL (range 0-14) was established by summing the scores of the poorest quartile for each of 14 biological variables related to the metabolic and immune systems. Results: We found a social gradient in AL in late midlife among men and women living in Denmark. Discussion: AL may be a potential biomarker for early aging in countries with a strong social welfare system. It is important for intervention studies to be aware of this type of biological vulnerability already present in late midlife.

AB - Objective: The objective of the present study is to describe the prevalence of allostatic load (AL) among Danish men and women in late midlife, and if there is a social gradient in AL. Method: A total of 5,420 participants from the Copenhagen Aging and Midlife Biobank (CAMB) aged 48 to 63 years (68.5% men, 31.5% women) underwent a health examination including standardized measures of height, weight, body fat, and blood pressure in 2009-2011. AL (range 0-14) was established by summing the scores of the poorest quartile for each of 14 biological variables related to the metabolic and immune systems. Results: We found a social gradient in AL in late midlife among men and women living in Denmark. Discussion: AL may be a potential biomarker for early aging in countries with a strong social welfare system. It is important for intervention studies to be aware of this type of biological vulnerability already present in late midlife.

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DO - 10.1177/0898264313508187

M3 - Journal article

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SP - 72

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JO - Journal of Aging and Health

JF - Journal of Aging and Health

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ER -

Social gradient in allostatic load among Danish men and women in late midlife

Abstract

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