TY - JOUR
T1 - Serine-stretch protein (SERP) of Plasmodium falciparum corresponds to the exoantigen Ag2, a target of antibodies associated with protection against malaria
AU - Jakobsen, P H
AU - Hundt, E
AU - Hansen, Morten Bagge
AU - Knapp, B
N1 - Keywords: Amino Acid Sequence; Animals; Antibodies, Protozoan; Antigens, Protozoan; Antigens, Surface; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Humans; Immune Sera; Immunoblotting; Immunoelectrophoresis, Two-Dimensional; Malaria Vaccines; Malaria, Falciparum; Molecular Sequence Data; Proteins; Protozoan Proteins; Rabbits
PY - 1994
Y1 - 1994
N2 - A mixture of Plasmodium falciparum exoantigens inducing lymphocyte activation and cytokine production was shown to contain the malaria vaccine candidate, the serine-stretch protein. This protein was shown serologically to correspond to Ag2, an exoantigen recognized by antibodies linked with protection against malaria. The glycophorin-binding protein, the histidine-rich protein II, the S-antigen, the heat shock protein 70, the ring-infected erythrocyte surface antigen, and the apical membrane antigen-1 were also shown serologically to be present in the mixture of exoantigens.
AB - A mixture of Plasmodium falciparum exoantigens inducing lymphocyte activation and cytokine production was shown to contain the malaria vaccine candidate, the serine-stretch protein. This protein was shown serologically to correspond to Ag2, an exoantigen recognized by antibodies linked with protection against malaria. The glycophorin-binding protein, the histidine-rich protein II, the S-antigen, the heat shock protein 70, the ring-infected erythrocyte surface antigen, and the apical membrane antigen-1 were also shown serologically to be present in the mixture of exoantigens.
M3 - Journal article
C2 - 8167001
SN - 0903-4641
VL - 102
SP - 53
EP - 58
JO - Acta Pathologica Microbiologica et Immunologica Scandinavica
JF - Acta Pathologica Microbiologica et Immunologica Scandinavica
IS - 1
ER -
