Risiko for anastomoselækage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer: Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs

M. Klein; Ismayil Gögenür; J. Rosenberg

Risiko for anastomoselækage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer: Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs

3 Citationer (Scopus)

Abstract

Anastomotic leakage is the most serious complication following colorectal resection. Recently, focus has been on possible effects of non-steroidal anti-inflammatory drugs (NSAIDs). Animal studies have found a correlation between treatment with NSAIDs and increased leakage rate, impaired anastomotic strength and reduced deposition of hydroxyproline. Retrospective human studies have reported increased leakage rates after postoperative diclofenac and celecoxib treatment. We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis

Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	172
Udgave nummer	22
Sider (fra-til)	1660-1662
Antal sider	3
ISSN	0041-5782
Status	Udgivet - 2010

Citationsformater

Risiko for anastomoselækage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer : Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs. / Klein, M.; Gögenür, Ismayil ; Rosenberg, J.

I: Ugeskrift for Laeger, Bind 172, Nr. 22, 2010, s. 1660-1662.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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title = "Risiko for anastomosel{\ae}kage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer: Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs",

abstract = "Anastomotic leakage is the most serious complication following colorectal resection. Recently, focus has been on possible effects of non-steroidal anti-inflammatory drugs (NSAIDs). Animal studies have found a correlation between treatment with NSAIDs and increased leakage rate, impaired anastomotic strength and reduced deposition of hydroxyproline. Retrospective human studies have reported increased leakage rates after postoperative diclofenac and celecoxib treatment. We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis",

author = "M. Klein and Ismayil G{\"o}gen{\"u}r and J. Rosenberg",

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T1 - Risiko for anastomoselækage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer

T2 - Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs

AU - Klein, M.

AU - Gögenür, Ismayil

AU - Rosenberg, J.

PY - 2010

Y1 - 2010

N2 - Anastomotic leakage is the most serious complication following colorectal resection. Recently, focus has been on possible effects of non-steroidal anti-inflammatory drugs (NSAIDs). Animal studies have found a correlation between treatment with NSAIDs and increased leakage rate, impaired anastomotic strength and reduced deposition of hydroxyproline. Retrospective human studies have reported increased leakage rates after postoperative diclofenac and celecoxib treatment. We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis

AB - Anastomotic leakage is the most serious complication following colorectal resection. Recently, focus has been on possible effects of non-steroidal anti-inflammatory drugs (NSAIDs). Animal studies have found a correlation between treatment with NSAIDs and increased leakage rate, impaired anastomotic strength and reduced deposition of hydroxyproline. Retrospective human studies have reported increased leakage rates after postoperative diclofenac and celecoxib treatment. We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 172

SP - 1660

EP - 1662

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

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