Regulering af cytokindannelse ved inflammatoriske tarmsygdomme

Laura Ferrero-Miliani, Jakob Benecidt Seidelin, Ole Haagen Nielsen

    7 Citationer (Scopus)

    Abstract

    Interleukin-1beta (IL-1beta) is a pivotal mediator in the inflammatory immune response that is characteristic of a number of chronic disorders. The etiology and pathophysiology of inflammatory bowel disease (IBD) have for many years been an enigma. The recent identification of the inflammasome, a multiprotein complex responsible for interleukin-1beta converting enzyme (ICE, caspase-1) activation, has generated new possibilities for the elucidation of the etiology and pathophysiology of IBD and as a consequence also for the identification of new treatment targets.
    Bidragets oversatte titelRegulation of cytokine production in inflammatory bowel disease
    OriginalsprogDansk
    TidsskriftUgeskrift for Laeger
    Vol/bind168
    Udgave nummer19
    Sider (fra-til)1847-50
    Antal sider4
    ISSN0041-5782
    StatusUdgivet - 2006

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