Quantitation of RHD by real-time polymerase chain reaction for determination of RHD zygosity and RHD mosaicism/chimerism: an evaluation of four quantitative methods

Grethe Risum Krog, Frederik Banch Clausen, Morten Hanefeld Dziegiel

    14 Citationer (Scopus)

    Abstract

    Determination of RHD zygosity of the spouse is crucial in preconception counseling of families with history of hemolytic disease of the fetus and newborn caused by anti-D. RHD zygosity can be determined by quantitative real-time polymerase chain reaction (PCR) basically by determining RHD dosage, and this feature is relevant in investigating RHD mosaicism and chimerism.
    OriginalsprogEngelsk
    TidsskriftTransfusion
    Vol/bind47
    Udgave nummer4
    Sider (fra-til)715-22
    Antal sider8
    ISSN0041-1132
    DOI
    StatusUdgivet - apr. 2007

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