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Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Georgia Kasten, Íris Duarte, Maria Paisana,
Korbinian Löbmann
,
Thomas Rades
,
Holger Grohganz
7
Citationer (Scopus)
21
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Keyphrases
Amorphous Formulation
100%
Amorphization
100%
Process Optimization
100%
Process Upscaling
100%
Amino Acids
100%
F Atoms
80%
Spray Drying
40%
Gas Flow Rate
40%
Amorphous Indomethacin
20%
Spray Dryer
20%
Critical Quality Attributes
20%
Lysine
20%
Glass Transition Temperature
20%
Chamber Geometry
20%
Product Characteristics
20%
Design of Experiments
20%
Experiment Results
20%
Critical Process Parameters
20%
Particle Size Distribution
20%
Bulk Density
20%
Feed Flow Rate
20%
Residence Time
20%
Full-scale Experiment
20%
Small Particle Size
20%
Production Techniques
20%
Low Bulk Density
20%
Chemical Engineering
Atomizer Nozzle
100%