Jørgensen, D. E. S., Vejlstrup, N., Jørgensen, C., Maroun, L. L., Steensberg, J., Hessellund, A., Jørgensen, F. S., Larsen, T., Shalmi, A.-C., Skibsted, L., Zingenberg, H., Ekelund, C., & Tabor, A. (2015). Prenatal detection of congenital heart disease in a low risk population undergoing first and second trimester screening. Prenatal Diagnosis, 35(4), 325-30. https://doi.org/10.1002/pd.4525
Prenatal detection of congenital heart disease in a low risk population undergoing first and second trimester screening. / Jørgensen, Ditte E S; Vejlstrup, Niels; Jørgensen, Connie et al.
I:
Prenatal Diagnosis, Bind 35, Nr. 4, 01.04.2015, s. 325-30.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Jørgensen, DES, Vejlstrup, N, Jørgensen, C, Maroun, LL, Steensberg, J, Hessellund, A, Jørgensen, FS, Larsen, T, Shalmi, A-C, Skibsted, L, Zingenberg, H, Ekelund, C & Tabor, A 2015, 'Prenatal detection of congenital heart disease in a low risk population undergoing first and second trimester screening', Prenatal Diagnosis, bind 35, nr. 4, s. 325-30. https://doi.org/10.1002/pd.4525
Jørgensen DES, Vejlstrup N, Jørgensen C, Maroun LL, Steensberg J, Hessellund A et al. Prenatal detection of congenital heart disease in a low risk population undergoing first and second trimester screening. Prenatal Diagnosis. 2015 apr. 1;35(4):325-30. doi: 10.1002/pd.4525
Jørgensen, Ditte E S ; Vejlstrup, Niels ; Jørgensen, Connie et al. / Prenatal detection of congenital heart disease in a low risk population undergoing first and second trimester screening. I: Prenatal Diagnosis. 2015 ; Bind 35, Nr. 4. s. 325-30.
@article{fb0d55bb3b1e483b988baced30bf41bc,
title = "Prenatal detection of congenital heart disease in a low risk population undergoing first and second trimester screening",
abstract = "Objectives: The prenatal detection rate of congenital heart disease (CHD) is low compared with other fetal malformations. Our aim was to evaluate the prenatal detection of CHD in Eastern Denmark. Methods: Fetuses and infants diagnosed with CHD in the period 01.01.2008-31.12.2010 were assessed regarding prenatal detection rate and accuracy, as well as correlation with nuchal translucency (NT) thickness. Results: Out of 86121 infants, 831 were born with CHD (0.96%). The prenatal detection rate of 'all CHD' was 21.3%, of 'Major CHD' 47.4%. Full agreement between prenatal and postnatal/autopsy findings was found in 96% of prenatally detected diagnoses. An NT thickness >95th percentile was found in 15.0% fetuses with 'Major CHD'. Of 'Major CHDs' detected prenatally, 77% were picked up at the time of the malformation scan at weeks 18-21. Conclusions: Nearly half of 'Major CHDs' were detected prenatally. The prenatal cardiac diagnoses showed a high degree of accuracy. Increased NT thickness as a screening tool for CHD performed moderately but is an important high risk group for specialist examination. A minority of the prenatally detected CHDs was identified because of extra scans performed in high risk pregnancies.",
author = "J{\o}rgensen, {Ditte E S} and Niels Vejlstrup and Connie J{\o}rgensen and Maroun, {Lisa Leth} and Jesper Steensberg and Anette Hessellund and J{\o}rgensen, {Finn Stener} and Torben Larsen and Anne-Cathrine Shalmi and Lillian Skibsted and Helle Zingenberg and Charlotte Ekelund and Ann Tabor",
note = "{\textcopyright} 2014 John Wiley & Sons, Ltd.",
year = "2015",
month = apr,
day = "1",
doi = "10.1002/pd.4525",
language = "English",
volume = "35",
pages = "325--30",
journal = "Prenatal Diagnosis",
issn = "0197-3851",
publisher = "JohnWiley & Sons Ltd",
number = "4",
}
TY - JOUR
T1 - Prenatal detection of congenital heart disease in a low risk population undergoing first and second trimester screening
AU - Jørgensen, Ditte E S
AU - Vejlstrup, Niels
AU - Jørgensen, Connie
AU - Maroun, Lisa Leth
AU - Steensberg, Jesper
AU - Hessellund, Anette
AU - Jørgensen, Finn Stener
AU - Larsen, Torben
AU - Shalmi, Anne-Cathrine
AU - Skibsted, Lillian
AU - Zingenberg, Helle
AU - Ekelund, Charlotte
AU - Tabor, Ann
N1 - © 2014 John Wiley & Sons, Ltd.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Objectives: The prenatal detection rate of congenital heart disease (CHD) is low compared with other fetal malformations. Our aim was to evaluate the prenatal detection of CHD in Eastern Denmark. Methods: Fetuses and infants diagnosed with CHD in the period 01.01.2008-31.12.2010 were assessed regarding prenatal detection rate and accuracy, as well as correlation with nuchal translucency (NT) thickness. Results: Out of 86121 infants, 831 were born with CHD (0.96%). The prenatal detection rate of 'all CHD' was 21.3%, of 'Major CHD' 47.4%. Full agreement between prenatal and postnatal/autopsy findings was found in 96% of prenatally detected diagnoses. An NT thickness >95th percentile was found in 15.0% fetuses with 'Major CHD'. Of 'Major CHDs' detected prenatally, 77% were picked up at the time of the malformation scan at weeks 18-21. Conclusions: Nearly half of 'Major CHDs' were detected prenatally. The prenatal cardiac diagnoses showed a high degree of accuracy. Increased NT thickness as a screening tool for CHD performed moderately but is an important high risk group for specialist examination. A minority of the prenatally detected CHDs was identified because of extra scans performed in high risk pregnancies.
AB - Objectives: The prenatal detection rate of congenital heart disease (CHD) is low compared with other fetal malformations. Our aim was to evaluate the prenatal detection of CHD in Eastern Denmark. Methods: Fetuses and infants diagnosed with CHD in the period 01.01.2008-31.12.2010 were assessed regarding prenatal detection rate and accuracy, as well as correlation with nuchal translucency (NT) thickness. Results: Out of 86121 infants, 831 were born with CHD (0.96%). The prenatal detection rate of 'all CHD' was 21.3%, of 'Major CHD' 47.4%. Full agreement between prenatal and postnatal/autopsy findings was found in 96% of prenatally detected diagnoses. An NT thickness >95th percentile was found in 15.0% fetuses with 'Major CHD'. Of 'Major CHDs' detected prenatally, 77% were picked up at the time of the malformation scan at weeks 18-21. Conclusions: Nearly half of 'Major CHDs' were detected prenatally. The prenatal cardiac diagnoses showed a high degree of accuracy. Increased NT thickness as a screening tool for CHD performed moderately but is an important high risk group for specialist examination. A minority of the prenatally detected CHDs was identified because of extra scans performed in high risk pregnancies.
U2 - 10.1002/pd.4525
DO - 10.1002/pd.4525
M3 - Journal article
C2 - 25352400
SN - 0197-3851
VL - 35
SP - 325
EP - 330
JO - Prenatal Diagnosis
JF - Prenatal Diagnosis
IS - 4
ER -