Pregnancy-associated plasma protein-A and the vulnerable plaque

Camilla H B Jespersen; Kirstine R Vestergaard; Morten Schou; Børge Teisner; Jens P Goetze; Kasper Iversen

doi:10.2217/bmm.14.53

Pregnancy-associated plasma protein-A and the vulnerable plaque

Camilla H B Jespersen, Kirstine R Vestergaard, Morten Schou, Børge Teisner, Jens P Goetze, Kasper Iversen

Institut for Klinisk Medicin

5 Citationer (Scopus)

Abstract

For more than a decade, pregnancy-associated plasma protein-A (PAPP-A) has been examined for its relation to acute coronary syndrome (ACS) and the vulnerable plaque. This review summarizes the current knowledge of plasma PAPP-A in relation to nonpregnant individuals focusing on patients with ACS, discusses its use as a possible biomarker for diagnosis and prognosis in ACS, briefly describes the challenges in different assay technologies and describes the effect of heparin administration on PAPP-A concentrations in plasma.

Originalsprog	Engelsk
Tidsskrift	Biomarkers in Medicine
Vol/bind	8
Udgave nummer	8
Sider (fra-til)	1033-47
Antal sider	15
ISSN	1752-0363
DOI	https://doi.org/10.2217/bmm.14.53
Status	Udgivet - 1 aug. 2014

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10.2217/bmm.14.53

Citationsformater

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abstract = "For more than a decade, pregnancy-associated plasma protein-A (PAPP-A) has been examined for its relation to acute coronary syndrome (ACS) and the vulnerable plaque. This review summarizes the current knowledge of plasma PAPP-A in relation to nonpregnant individuals focusing on patients with ACS, discusses its use as a possible biomarker for diagnosis and prognosis in ACS, briefly describes the challenges in different assay technologies and describes the effect of heparin administration on PAPP-A concentrations in plasma.",

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AU - Jespersen, Camilla H B

AU - Vestergaard, Kirstine R

AU - Schou, Morten

AU - Teisner, Børge

AU - Goetze, Jens P

AU - Iversen, Kasper

PY - 2014/8/1

Y1 - 2014/8/1

N2 - For more than a decade, pregnancy-associated plasma protein-A (PAPP-A) has been examined for its relation to acute coronary syndrome (ACS) and the vulnerable plaque. This review summarizes the current knowledge of plasma PAPP-A in relation to nonpregnant individuals focusing on patients with ACS, discusses its use as a possible biomarker for diagnosis and prognosis in ACS, briefly describes the challenges in different assay technologies and describes the effect of heparin administration on PAPP-A concentrations in plasma.

AB - For more than a decade, pregnancy-associated plasma protein-A (PAPP-A) has been examined for its relation to acute coronary syndrome (ACS) and the vulnerable plaque. This review summarizes the current knowledge of plasma PAPP-A in relation to nonpregnant individuals focusing on patients with ACS, discusses its use as a possible biomarker for diagnosis and prognosis in ACS, briefly describes the challenges in different assay technologies and describes the effect of heparin administration on PAPP-A concentrations in plasma.

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DO - 10.2217/bmm.14.53

M3 - Journal article

C2 - 25343675

SN - 1752-0363

VL - 8

SP - 1033

EP - 1047

JO - Biomarkers in Medicine

JF - Biomarkers in Medicine

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ER -

Pregnancy-associated plasma protein-A and the vulnerable plaque

Abstract

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