Partial loss-of-function alleles reveal a role for GNOM in auxin transport-related, post-embryonic development of Arabidopsis

TY - JOUR

T1 - Partial loss-of-function alleles reveal a role for GNOM in auxin transport-related, post-embryonic development of Arabidopsis

AU - Geldner, Niko

AU - Richter, Sandra

AU - Vieten, Anne

AU - Marquardt, Sebastian

AU - Torres-Ruiz, Ramon A

AU - Mayer, Ulrike

AU - Jürgens, Gerd

PY - 2004/1

Y1 - 2004/1

N2 - The Arabidopsis GNOM gene encodes an ARF GDP/GTP exchange factor involved in embryonic axis formation and polar localisation of the auxin efflux regulator PIN1. To examine whether GNOM also plays a role in post-embryonic development and to clarify its involvement in auxin transport, we have characterised newly isolated weak gnom alleles as well as trans-heterozygotes of complementing strong alleles. These genotypes form a phenotypic series of GNOM activity in post-embryonic development, with auxin-related defects, especially in the maintenance of primary root meristem activity and in the initiation and organisation of lateral root primordia. Our results suggest a model for GNOM action mediating auxin transport in both embryogenesis and post-embryonic organ development.

AB - The Arabidopsis GNOM gene encodes an ARF GDP/GTP exchange factor involved in embryonic axis formation and polar localisation of the auxin efflux regulator PIN1. To examine whether GNOM also plays a role in post-embryonic development and to clarify its involvement in auxin transport, we have characterised newly isolated weak gnom alleles as well as trans-heterozygotes of complementing strong alleles. These genotypes form a phenotypic series of GNOM activity in post-embryonic development, with auxin-related defects, especially in the maintenance of primary root meristem activity and in the initiation and organisation of lateral root primordia. Our results suggest a model for GNOM action mediating auxin transport in both embryogenesis and post-embryonic organ development.

KW - Alleles

KW - Arabidopsis

KW - Arabidopsis Proteins

KW - Biological Transport, Active

KW - Gene Expression Regulation, Developmental

KW - Gene Expression Regulation, Plant

KW - Genes, Plant

KW - Gravitropism

KW - Guanine Nucleotide Exchange Factors

KW - Indoleacetic Acids

KW - Meristem

KW - Models, Biological

KW - Mutation

KW - Phenotype

KW - Plant Growth Regulators

KW - Plant Roots

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1242/dev.00926

DO - 10.1242/dev.00926

M3 - Journal article

C2 - 14681187

SN - 0950-1991

VL - 131

SP - 389

EP - 400

JO - Development (Cambridge, England)

JF - Development (Cambridge, England)

IS - 2

ER -