Parasitaere sygdomme hos patienter med nedsat immunforsvar. Klinisk billede og diagnose

TY - JOUR

T1 - Parasitaere sygdomme hos patienter med nedsat immunforsvar. Klinisk billede og diagnose

AU - Petersen, E

AU - Lebech, M

AU - Højlyng, N

AU - Holten-Andersen, W

AU - Mølbak, K

AU - Høgh, B

AU - Jepsen, S

PY - 1992/9/7

Y1 - 1992/9/7

N2 - Patients with impaired immune system are frequently infected with various parasitic diseases. The clinical picture is characterized by unusual manifestations and frequently severe recurrences of infections which are not normally serious. Some almost parasitic microorganisms produce symptoms exclusively in patients with impaired immune system. Parasitic infections have become increasingly common with the increasing number of patients who live for prolonged periods with impaired immune systems, often as a result of infection with HIV. Among the numerous parasitic infections which are observed in man, there are a few which occur particularly frequently in patients with impaired immune systems. This is a brief review of the clinical pictures and diagnostic options in parasitic disease in individuals with impaired immune system with particular emphasis on infections caused by: Pneumocystis carinii, Toxoplasma gondii, Cryptosporidium ssp., Microspora, Entamoeba histolytica, Leishmania ssp., and Strongyloides stercoralis. In patients with impaired immunity, parasitic infections frequently cause nonspecific symptoms and, on account of the impaired immunity, antibodies to the parasite are not always produced. The diagnosis of these infections is, therefore, based on morphological demonstration of the microorganism concerned, culture, specific antigen or DNA defections.

AB - Patients with impaired immune system are frequently infected with various parasitic diseases. The clinical picture is characterized by unusual manifestations and frequently severe recurrences of infections which are not normally serious. Some almost parasitic microorganisms produce symptoms exclusively in patients with impaired immune system. Parasitic infections have become increasingly common with the increasing number of patients who live for prolonged periods with impaired immune systems, often as a result of infection with HIV. Among the numerous parasitic infections which are observed in man, there are a few which occur particularly frequently in patients with impaired immune systems. This is a brief review of the clinical pictures and diagnostic options in parasitic disease in individuals with impaired immune system with particular emphasis on infections caused by: Pneumocystis carinii, Toxoplasma gondii, Cryptosporidium ssp., Microspora, Entamoeba histolytica, Leishmania ssp., and Strongyloides stercoralis. In patients with impaired immunity, parasitic infections frequently cause nonspecific symptoms and, on account of the impaired immunity, antibodies to the parasite are not always produced. The diagnosis of these infections is, therefore, based on morphological demonstration of the microorganism concerned, culture, specific antigen or DNA defections.

KW - Acquired Immunodeficiency Syndrome/immunology

KW - Cestode Infections/diagnosis

KW - HIV Seropositivity/immunology

KW - Humans

KW - Immunologic Deficiency Syndromes/immunology

KW - Nematode Infections/diagnosis

KW - Parasitic Diseases/diagnosis

KW - Protozoan Infections/diagnosis

KW - Trematode Infections/diagnosis

M3 - Review

C2 - 1413170

SN - 0041-5782

VL - 154

SP - 2475

EP - 2480

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 37

ER -