Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

D. Ehmann; J. Wendler; L. Koeninger; I. S. Larsen; T. Klag; J. Berger; A. Marette; M. Schaller; E. F. Stange; N. P. Malek; B. A. H. Jensen; J. Wehkamp

doi:10.1073/pnas.1817376116

Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

D. Ehmann, J. Wendler, L. Koeninger, I. S. Larsen, T. Klag, J. Berger, A. Marette, M. Schaller, E. F. Stange, N. P. Malek, B. A. H. Jensen, J. Wehkamp

24 Citationer (Scopus)

Originalsprog	Engelsk
Tidsskrift	Proceedings of the National Academy of Sciences of the United States of America
Vol/bind	116
Udgave nummer	9
Sider (fra-til)	3746-3751
ISSN	0027-8424
DOI	https://doi.org/10.1073/pnas.1817376116
Status	Udgivet - 26 feb. 2019

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10.1073/pnas.1817376116

3746.full.pdfForlagets udgivne version, 1,19 MBLicens: CC BY-NC-ND

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Ehmann, D., Wendler, J., Koeninger, L., Larsen, I. S., Klag, T., Berger, J., Marette, A., Schaller, M., Stange, E. F., Malek, N. P., Jensen, B. A. H., & Wehkamp, J. (2019). Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments. Proceedings of the National Academy of Sciences of the United States of America, 116(9), 3746-3751. https://doi.org/10.1073/pnas.1817376116

Ehmann, D, Wendler, J, Koeninger, L, Larsen, IS, Klag, T, Berger, J, Marette, A, Schaller, M, Stange, EF, Malek, NP, Jensen, BAH & Wehkamp, J 2019, 'Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments', Proceedings of the National Academy of Sciences of the United States of America, bind 116, nr. 9, s. 3746-3751. https://doi.org/10.1073/pnas.1817376116

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title = "Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments",

keywords = "antimicrobial peptides, alpha-defensins, intestinal barrier, proteolytic digestion, host-microbiota interaction",

author = "D. Ehmann and J. Wendler and L. Koeninger and Larsen, {I. S.} and T. Klag and J. Berger and A. Marette and M. Schaller and Stange, {E. F.} and Malek, {N. P.} and Jensen, {B. A. H.} and J. Wehkamp",

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doi = "10.1073/pnas.1817376116",

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TY - JOUR

T1 - Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

AU - Ehmann, D.

AU - Wendler, J.

AU - Koeninger, L.

AU - Larsen, I. S.

AU - Klag, T.

AU - Berger, J.

AU - Marette, A.

AU - Schaller, M.

AU - Stange, E. F.

AU - Malek, N. P.

AU - Jensen, B. A. H.

AU - Wehkamp, J.

PY - 2019/2/26

Y1 - 2019/2/26

KW - antimicrobial peptides

KW - alpha-defensins

KW - intestinal barrier

KW - proteolytic digestion

KW - host-microbiota interaction

U2 - 10.1073/pnas.1817376116

DO - 10.1073/pnas.1817376116

M3 - Journal article

C2 - 30808760

SN - 0027-8424

VL - 116

SP - 3746

EP - 3751

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 9

ER -

Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

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