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Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation
Martin D Rees, David I Pattison,
Michael Jonathan Davies
49
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Medicin og biovidenskab
Hypochlorous Acid
100%
Heparitin Sulfate
85%
Chloramines
83%
Glycosaminoglycans
74%
Peroxidase
67%
Glucosamine
57%
Polymers
41%
perlecan
35%
Glypicans
34%
Acetylglucosamine
30%
Monosaccharides
29%
Heparan Sulfate Proteoglycans
29%
Respiratory Burst
28%
Heme
25%
Proteoglycans
25%
Anions
24%
Phagocytes
24%
Superoxides
23%
Extracellular Matrix
19%
Enzymes
12%
N-chlorosulfonamide
7%
Kemiske forbindelser
Heparan Sulfate
89%
Hypochlorite
85%
Glycosaminoglycan
81%
Chloramine
66%
Fragmentation
57%
Heparan Sulfate Proteoglycan
35%
Oxidation Reaction
31%
Hypochlorous Acid
30%
Proteoglycan
28%
N-Acetylglucosamine
28%
Glucosamine
26%
Monosaccharide
24%
Reaction Yield
18%
Rate Constant
15%
Anion
13%
Mixture
10%
pH Value
9%
Surface
7%