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Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation
Martin D Rees, David I Pattison,
Michael Jonathan Davies
49
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Medicin og biovidenskab
Acetylglucosamine
30%
Anions
24%
Chloramines
83%
Enzymes
12%
Extracellular Matrix
19%
Glucosamine
57%
Glycosaminoglycans
74%
Glypicans
34%
Heme
25%
Heparan Sulfate Proteoglycans
29%
Heparitin Sulfate
85%
Hypochlorous Acid
100%
Monosaccharides
29%
N-chlorosulfonamide
7%
perlecan
35%
Peroxidase
67%
Phagocytes
24%
Polymers
41%
Proteoglycans
25%
Respiratory Burst
28%
Superoxides
23%
Kemiske forbindelser
Anion
13%
Chloramine
66%
Fragmentation
57%
Glucosamine
26%
Glycosaminoglycan
81%
Heparan Sulfate
89%
Heparan Sulfate Proteoglycan
35%
Hypochlorite
85%
Hypochlorous Acid
30%
Mixture
10%
Monosaccharide
24%
N-Acetylglucosamine
28%
Oxidation Reaction
31%
pH Value
9%
Proteoglycan
28%
Rate Constant
15%
Reaction Yield
18%
Surface
7%