Oxalyl chloride as a practical carbon monoxide source for carbonylation reactions

TY - JOUR

T1 - Oxalyl chloride as a practical carbon monoxide source for carbonylation reactions

AU - Hansen, Steffen V F

AU - Ulven, Trond

PY - 2015/6/5

Y1 - 2015/6/5

N2 - A method for generation of high-quality carbon monoxide by decomposition of oxalyl chloride in an aqueous hydroxide solution is described. The usefulness of the method is demonstrated in the synthesis of heterocycles and for hydroxy-, alkoxy-, amino-, and reductive carbonylation reactions, in several cases under milder conditions than previously reported.

AB - A method for generation of high-quality carbon monoxide by decomposition of oxalyl chloride in an aqueous hydroxide solution is described. The usefulness of the method is demonstrated in the synthesis of heterocycles and for hydroxy-, alkoxy-, amino-, and reductive carbonylation reactions, in several cases under milder conditions than previously reported.

U2 - 10.1021/acs.orglett.5b01252

DO - 10.1021/acs.orglett.5b01252

M3 - Journal article

SN - 1523-7060

VL - 17

SP - 2832

EP - 2835

JO - Organic Letters

JF - Organic Letters

IS - 11

ER -