@article{2fea281049c611ddb7b4000ea68e967b,
title = "Origin of introns by 'intronization' of exonic sequences.",
abstract = "The mechanisms of spliceosomal intron creation have proved elusive. Here we describe a new mechanism: the recruitment of internal exonic sequences ('intronization') in Caenorhabditis species. The numbers of intronization events and introns gained by other mechanisms are similar, suggesting that intronization significantly contributes to recent intron creation in nematodes. Intronization is more common than the reverse process, loss of splicing of retained introns. Finally, these findings link alternative splicing with modern intron creation.",
author = "Manuel Irimia and Rukov, {Jakob Lewin} and David Penny and Jeppe Vinther and Jordi Garcia-Fernandez and Roy, {Scott William}",
year = "2008",
doi = "10.1016/j.tig.2008.05.007",
language = "English",
journal = "Trends in Genetics",
issn = "0168-9525",
publisher = "Elsevier Ltd. * Trends Journals",
}