Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform

Tobias Melton Axelsen; Charlotte Amalie Emdal Navntoft; Søren Hofman Christiansen; Jakob Kisbye Dreyer; Jakob Balslev Sørensen; Ulrik Gether; David Paul Drucker Woldbye

Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform

Tobias Melton Axelsen, Charlotte Amalie Emdal Navntoft, Søren Hofman Christiansen, Jakob Kisbye Dreyer, Jakob Balslev Sørensen, Ulrik Gether, David Paul Drucker Woldbye

Abstract

Optogenetics is an emergent technology that combines light-sensitive proteins derived from algae, so-called opsins, with genetics. Viral vectors encoding opsins are injected into selective brain regions whereby specific cell populations can be controlled with high precision light pulses delivered via implanted optical fibres. This review focuses on explaining basic principles of optogenetics and describes important insights into neuropsychiatric mechanisms provided by the technology.

Bidragets oversatte titel	Optogenetics brings hidden neural mechanisms into the light and could become a future therapy
Originalsprog	Dansk
Artikelnummer	V06150501
Tidsskrift	Ugeskrift for Laeger
Vol/bind	177
Udgave nummer	34
Sider (fra-til)	2-5
Antal sider	4
ISSN	0041-5782
Status	Udgivet - 17 aug. 2015

Citationsformater

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AU - Axelsen, Tobias Melton

AU - Navntoft, Charlotte Amalie Emdal

AU - Christiansen, Søren Hofman

AU - Dreyer, Jakob Kisbye

AU - Sørensen, Jakob Balslev

AU - Gether, Ulrik

AU - Woldbye, David Paul Drucker

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Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform

Abstract

Fingeraftryk

Citationsformater