@article{0cbbccf0117e11df803f000ea68e967b,
title = "One-year mortality in coagulase-negative Staphylococcus and Staphylococcus aureus infective endocarditis",
abstract = "The aim of this study was to investigate in-hospital mortality and 12-month mortality in patients with coagulase-negative Staphylococcus (CoNS) compared to Staphylococcus aureus (S. aureus) infective endocarditis (IE). We used a prospective cohort study of 66 consecutive CoNS and 170 S. aureus IE patients, collected at 2 tertiary university hospitals in Copenhagen (Denmark) and at 1 tertiary university hospital in Gothenburg (Sweden). Median (range) C-reactive protein at admission was higher in patients with S. aureus IE (150 mg/l (1-521) vs 94 mg/l (6-303); p<0.001), which may suggest a more serous infection. CoNS was associated with prosthetic valve IE (49% vs 24%; p<0.001) and median diagnostic delay was longer in CoNS IE patients (20 d (0-232) vs 9 d (0-132); p<0.001). In-hospital mortality was equally high in both groups but 25% of the CoNS IE patients had died after 1 y compared to 39% of patients with S. aureus IE (p =0.05). In conclusion, CoNS IE was associated with a long diagnostic delay and high in-hospital mortality, whereas post-discharge prognosis was better in this group of patients compared to patients with IE due to S. aureus.",
author = "Rasmussen, {Rasmus V} and Ulrika Snygg-Martin and Lars Olaison and Rune Andersson and Kristine Buchholtz and Larsen, {Carsten T} and Hansen, {Thomas F} and Lars K{\o}ber and Christian Hassager and Bruun, {Niels E} and Rasmussen, {Rasmus V} and Ulrika Snygg-Martin and Lars Olaison and Rune Andersson and Kristine Buchholtz and Larsen, {Carsten T} and Hansen, {Thomas Fritz} and Lars K{\o}ber and Christian Hassager and Bruun, {Niels E}",
year = "2009",
month = jan,
day = "1",
doi = "10.1080/00365540902896061",
language = "English",
volume = "41",
pages = "456--61",
journal = "Scandinavian Journal of Infectious Diseases, Supplement",
issn = "0300-8878",
publisher = "Taylor & Francis",
number = "6-7",
}