Oct4: the final frontier, differentiation defining pluripotency

Alessandra Livigni, Joshua M Brickman

5 Citationer (Scopus)

Abstract

The transcription factor OCT4 is a cornerstone of pluripotency, and yet OCT4 has also been associated with differentiation in a number of contexts. Reporting in this issue of Developmental Cell, Frum et al. (2013) show that OCT4's major early activity in the blastocyst is to support primitive endoderm differentiation.
OriginalsprogEngelsk
TidsskriftDevelopmental Cell
Vol/bind25
Udgave nummer6
Sider (fra-til)547-8
Antal sider2
DOI
StatusUdgivet - 24 jun. 2013

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