Abstract
We present an anatomically guided feature selection scheme for prediction of neurological disorders based on brain connectivity networks. Using anatomical information not only gives rise to an interpretable model, but also prevents overfitting, caused by high dimensionality, noise and correlated features. Our method selects meaningful and discriminative groups of connections between anatomical regions, which can be used as input for any supervised classifier, such as logistic regression or a support vector machine. We demonstrate the effectiveness of our method on a dataset of autism spectrum disorder, with an AUC of 0.76, outperforming baseline methods.
Originalsprog | Engelsk |
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Titel | Machine learning in medical imaging : 5th International Workshop, MLMI 2014, Held in Conjunction with MICCAI 2014, Boston, MA, USA, September 14, 2014. Proceedings |
Redaktører | Guorong Wu, Daoqiang Zhang, Luping Zhou |
Antal sider | 8 |
Forlag | Springer |
Publikationsdato | 2014 |
Sider | 190-197 |
Kapitel | 24 |
ISBN (Trykt) | 978-3-319-10580-2 |
ISBN (Elektronisk) | 978-3-319-10581-9 |
DOI | |
Status | Udgivet - 2014 |
Begivenhed | 5th International Workshop on Machine Learning in Medical Imaging - Boston, USA Varighed: 14 sep. 2014 → 14 sep. 2014 Konferencens nummer: 5 |
Konference
Konference | 5th International Workshop on Machine Learning in Medical Imaging |
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Nummer | 5 |
Land/Område | USA |
By | Boston |
Periode | 14/09/2014 → 14/09/2014 |
Navn | Lecture notes in computer science |
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Vol/bind | 8679 |
ISSN | 0302-9743 |