Abstract
We present an anatomically guided feature selection scheme for prediction of neurological disorders based on brain connectivity networks. Using anatomical information not only gives rise to an interpretable model, but also prevents overfitting, caused by high dimensionality, noise and correlated features. Our method selects meaningful and discriminative groups of connections between anatomical regions, which can be used as input for any supervised classifier, such as logistic regression or a support vector machine. We demonstrate the effectiveness of our method on a dataset of autism spectrum disorder, with an AUC of 0.76, outperforming baseline methods.
Original language | English |
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Title of host publication | Machine learning in medical imaging : 5th International Workshop, MLMI 2014, Held in Conjunction with MICCAI 2014, Boston, MA, USA, September 14, 2014. Proceedings |
Editors | Guorong Wu, Daoqiang Zhang, Luping Zhou |
Number of pages | 8 |
Publisher | Springer |
Publication date | 2014 |
Pages | 190-197 |
Chapter | 24 |
ISBN (Print) | 978-3-319-10580-2 |
ISBN (Electronic) | 978-3-319-10581-9 |
DOIs | |
Publication status | Published - 2014 |
Event | 5th International Workshop on Machine Learning in Medical Imaging - Boston, United States Duration: 14 Sept 2014 → 14 Sept 2014 Conference number: 5 |
Conference
Conference | 5th International Workshop on Machine Learning in Medical Imaging |
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Number | 5 |
Country/Territory | United States |
City | Boston |
Period | 14/09/2014 → 14/09/2014 |
Series | Lecture notes in computer science |
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Volume | 8679 |
ISSN | 0302-9743 |