Network-guided group feature selection for classification of autism spectrum disorder

Veronika Cheplygina, David M.J. Tax, Marco Loog, Aasa Feragen

3 Citations (Scopus)

Abstract

We present an anatomically guided feature selection scheme for prediction of neurological disorders based on brain connectivity networks. Using anatomical information not only gives rise to an interpretable model, but also prevents overfitting, caused by high dimensionality, noise and correlated features. Our method selects meaningful and discriminative groups of connections between anatomical regions, which can be used as input for any supervised classifier, such as logistic regression or a support vector machine. We demonstrate the effectiveness of our method on a dataset of autism spectrum disorder, with an AUC of 0.76, outperforming baseline methods.

Original languageEnglish
Title of host publicationMachine learning in medical imaging : 5th International Workshop, MLMI 2014, Held in Conjunction with MICCAI 2014, Boston, MA, USA, September 14, 2014. Proceedings
EditorsGuorong Wu, Daoqiang Zhang, Luping Zhou
Number of pages8
PublisherSpringer
Publication date2014
Pages190-197
Chapter24
ISBN (Print)978-3-319-10580-2
ISBN (Electronic)978-3-319-10581-9
DOIs
Publication statusPublished - 2014
Event5th International Workshop on Machine Learning in Medical Imaging - Boston, United States
Duration: 14 Sept 201414 Sept 2014
Conference number: 5

Conference

Conference5th International Workshop on Machine Learning in Medical Imaging
Number5
Country/TerritoryUnited States
CityBoston
Period14/09/201414/09/2014
SeriesLecture notes in computer science
Volume8679
ISSN0302-9743

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