Abstract
Introduction: An optimal transfusion strategy for patients with upper gastrointestinal bleeding (UGIB) has yet tbe established. The national guidelines contain recommendations for patients with life-threating bleeding in general, but no specific recommendations for patients with UGIB. We hypothesised that there are variations in transfusion strategies for patients with UGIB across the Danish regions. Methods: We performed a retrospective, register-based, analysis on transfusions given to all patients with nonvariceal UGIB in Denmark in 2011-2013. We compared the results from the five regions in Denmark in order to discover regional differences. Results: A total of 5,292 admissions with treatment for non-variceal UGIB were identified, and analysis was made for the total group and a massive transfusions group (330 admissions). In the Capital Region, transfusion of platelets was more likely than in any other region for all patients (p < 0.01) including the massive transfusion group (p = 0.03). In the North Region, transfusion of fresh frozen plasma was more likely for the massive transfusion group (p = 0.01). Conclusion: The observed differences warrant further prospective cohort studies in order to provide a foundation for transfusion recommendations for patients with UGIB. Funding: none. Trial registration: not relevant.
| Originalsprog | Engelsk |
|---|---|
| Artikelnummer | A5296 |
| Tidsskrift | Danish Medical Journal |
| Vol/bind | 63 |
| Udgave nummer | 11 |
| Antal sider | 4 |
| ISSN | 1603-9629 |
| Status | Udgivet - nov. 2016 |