Mutation analysis of the MCHR1 gene in human obesity

Anne-Kathrin Wermter; Kathrin Reichwald; Thomas Büch; Frank Geller; Cornelia Platzer; Klaus Huse; Claudia Hess; Helmut Remschmidt; Thomas Gudermann; Gerald Preibisch; Wolfgang Siegfried; Hans-Peter Goldschmidt; Wei-Dong Li; R Arlen Price; Heike Biebermann; Heiko Krude; Caren Vollmert; H-Erich Wichmann; Thomas Illig; Thorkild I A Sørensen; Arne Astrup; Lesli Hingstrup Larsen; Oluf Pedersen; Delphine Eberlé; Karine Clément; John Blundell; Martin Wabitsch; Helmut Schäfer; Matthias Platzer; Anke Hinney; Johannes Hebebrand

doi:10.1530/eje.1.01917

Mutation analysis of the MCHR1 gene in human obesity

Anne-Kathrin Wermter, Kathrin Reichwald, Thomas Büch, Frank Geller, Cornelia Platzer, Klaus Huse, Claudia Hess, Helmut Remschmidt, Thomas Gudermann, Gerald Preibisch, Wolfgang Siegfried, Hans-Peter Goldschmidt, Wei-Dong Li, R Arlen Price, Heike Biebermann, Heiko Krude, Caren Vollmert, H-Erich Wichmann, Thomas Illig, Thorkild I A SørensenArne Astrup, Lesli Hingstrup Larsen, Oluf Pedersen, Delphine Eberlé, Karine Clément, John Blundell, Martin Wabitsch, Helmut Schäfer, Matthias Platzer, Anke Hinney, Johannes Hebebrand

31 Citationer (Scopus)

Abstract

The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.

Originalsprog	Engelsk
Tidsskrift	European Journal of Endocrinology
Vol/bind	152
Udgave nummer	6
Sider (fra-til)	851-62
Antal sider	12
ISSN	0804-4643
DOI	https://doi.org/10.1530/eje.1.01917
Status	Udgivet - 2005

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Wermter, A-K., Reichwald, K., Büch, T., Geller, F., Platzer, C., Huse, K., Hess, C., Remschmidt, H., Gudermann, T., Preibisch, G., Siegfried, W., Goldschmidt, H-P., Li, W-D., Price, R. A., Biebermann, H., Krude, H., Vollmert, C., Wichmann, H-E., Illig, T., ... Hebebrand, J. (2005). Mutation analysis of the MCHR1 gene in human obesity. European Journal of Endocrinology, 152(6), 851-62. https://doi.org/10.1530/eje.1.01917

Wermter, A-K, Reichwald, K, Büch, T, Geller, F, Platzer, C, Huse, K, Hess, C, Remschmidt, H, Gudermann, T, Preibisch, G, Siegfried, W, Goldschmidt, H-P, Li, W-D, Price, RA, Biebermann, H, Krude, H, Vollmert, C, Wichmann, H-E, Illig, T, Sørensen, TIA, Astrup, A, Larsen, LH, Pedersen, O, Eberlé, D, Clément, K, Blundell, J, Wabitsch, M, Schäfer, H, Platzer, M, Hinney, A & Hebebrand, J 2005, 'Mutation analysis of the MCHR1 gene in human obesity', European Journal of Endocrinology, bind 152, nr. 6, s. 851-62. https://doi.org/10.1530/eje.1.01917

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title = "Mutation analysis of the MCHR1 gene in human obesity",

abstract = "The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.",

keywords = "Adolescent, Adult, Animals, COS Cells, Cercopithecus aethiops, Cyclic AMP, DNA, Female, Humans, Inositol Phosphates, Male, Mitogen-Activated Protein Kinases, Obesity, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Polymorphism, Single Nucleotide, Polymorphism, Single-Stranded Conformational, Receptors, Pituitary Hormone, Sequence Analysis, DNA",

author = "Anne-Kathrin Wermter and Kathrin Reichwald and Thomas B{\"u}ch and Frank Geller and Cornelia Platzer and Klaus Huse and Claudia Hess and Helmut Remschmidt and Thomas Gudermann and Gerald Preibisch and Wolfgang Siegfried and Hans-Peter Goldschmidt and Wei-Dong Li and Price, {R Arlen} and Heike Biebermann and Heiko Krude and Caren Vollmert and H-Erich Wichmann and Thomas Illig and S{\o}rensen, {Thorkild I A} and Arne Astrup and Larsen, {Lesli Hingstrup} and Oluf Pedersen and Delphine Eberl{\'e} and Karine Cl{\'e}ment and John Blundell and Martin Wabitsch and Helmut Sch{\"a}fer and Matthias Platzer and Anke Hinney and Johannes Hebebrand",

year = "2005",

doi = "10.1530/eje.1.01917",

language = "English",

volume = "152",

pages = "851--62",

journal = "European Journal of Endocrinology",

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T1 - Mutation analysis of the MCHR1 gene in human obesity

AU - Wermter, Anne-Kathrin

AU - Reichwald, Kathrin

AU - Büch, Thomas

AU - Geller, Frank

AU - Platzer, Cornelia

AU - Huse, Klaus

AU - Hess, Claudia

AU - Remschmidt, Helmut

AU - Gudermann, Thomas

AU - Preibisch, Gerald

AU - Siegfried, Wolfgang

AU - Goldschmidt, Hans-Peter

AU - Li, Wei-Dong

AU - Price, R Arlen

AU - Biebermann, Heike

AU - Krude, Heiko

AU - Vollmert, Caren

AU - Wichmann, H-Erich

AU - Illig, Thomas

AU - Sørensen, Thorkild I A

AU - Astrup, Arne

AU - Larsen, Lesli Hingstrup

AU - Pedersen, Oluf

AU - Eberlé, Delphine

AU - Clément, Karine

AU - Blundell, John

AU - Wabitsch, Martin

AU - Schäfer, Helmut

AU - Platzer, Matthias

AU - Hinney, Anke

AU - Hebebrand, Johannes

PY - 2005

Y1 - 2005

N2 - The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.

AB - The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.

KW - Adolescent

KW - Adult

KW - Animals

KW - COS Cells

KW - Cercopithecus aethiops

KW - Cyclic AMP

KW - DNA

KW - Female

KW - Humans

KW - Inositol Phosphates

KW - Male

KW - Mitogen-Activated Protein Kinases

KW - Obesity

KW - Polymerase Chain Reaction

KW - Polymorphism, Restriction Fragment Length

KW - Polymorphism, Single Nucleotide

KW - Polymorphism, Single-Stranded Conformational

KW - Receptors, Pituitary Hormone

KW - Sequence Analysis, DNA

U2 - 10.1530/eje.1.01917

DO - 10.1530/eje.1.01917

M3 - Journal article

C2 - 15941924

SN - 0804-4643

VL - 152

SP - 851

EP - 862

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

IS - 6

ER -

Mutation analysis of the MCHR1 gene in human obesity

Abstract

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