Mutation analysis of the MCHR1 gene in human obesity

Anne-Kathrin Wermter; Kathrin Reichwald; Thomas Büch; Frank Geller; Cornelia Platzer; Klaus Huse; Claudia Hess; Helmut Remschmidt; Thomas Gudermann; Gerald Preibisch; Wolfgang Siegfried; Hans-Peter Goldschmidt; Wei-Dong Li; R Arlen Price; Heike Biebermann; Heiko Krude; Caren Vollmert; H-Erich Wichmann; Thomas Illig; Thorkild I A Sørensen; Arne Astrup; Lesli Hingstrup Larsen; Oluf Pedersen; Delphine Eberlé; Karine Clément; John Blundell; Martin Wabitsch; Helmut Schäfer; Matthias Platzer; Anke Hinney; Johannes Hebebrand

doi:10.1530/eje.1.01917

Mutation analysis of the MCHR1 gene in human obesity

Anne-Kathrin Wermter, Kathrin Reichwald, Thomas Büch, Frank Geller, Cornelia Platzer, Klaus Huse, Claudia Hess, Helmut Remschmidt, Thomas Gudermann, Gerald Preibisch, Wolfgang Siegfried, Hans-Peter Goldschmidt, Wei-Dong Li, R Arlen Price, Heike Biebermann, Heiko Krude, Caren Vollmert, H-Erich Wichmann, Thomas Illig, Thorkild I A SørensenArne Astrup, Lesli Hingstrup Larsen, Oluf Pedersen, Delphine Eberlé, Karine Clément, John Blundell, Martin Wabitsch, Helmut Schäfer, Matthias Platzer, Anke Hinney, Johannes Hebebrand

31 Citations (Scopus)

Abstract

The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.

Original language	English
Journal	European Journal of Endocrinology
Volume	152
Issue number	6
Pages (from-to)	851-62
Number of pages	12
ISSN	0804-4643
DOIs	https://doi.org/10.1530/eje.1.01917
Publication status	Published - 2005

Keywords

Adolescent
Adult
Animals
COS Cells
Cercopithecus aethiops
Cyclic AMP
DNA
Female
Humans
Inositol Phosphates
Male
Mitogen-Activated Protein Kinases
Obesity
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Polymorphism, Single Nucleotide
Polymorphism, Single-Stranded Conformational
Receptors, Pituitary Hormone
Sequence Analysis, DNA

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1530/eje.1.01917

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Wermter, A-K., Reichwald, K., Büch, T., Geller, F., Platzer, C., Huse, K., Hess, C., Remschmidt, H., Gudermann, T., Preibisch, G., Siegfried, W., Goldschmidt, H-P., Li, W-D., Price, R. A., Biebermann, H., Krude, H., Vollmert, C., Wichmann, H-E., Illig, T., ... Hebebrand, J. (2005). Mutation analysis of the MCHR1 gene in human obesity. European Journal of Endocrinology, 152(6), 851-62. https://doi.org/10.1530/eje.1.01917

Wermter, A-K, Reichwald, K, Büch, T, Geller, F, Platzer, C, Huse, K, Hess, C, Remschmidt, H, Gudermann, T, Preibisch, G, Siegfried, W, Goldschmidt, H-P, Li, W-D, Price, RA, Biebermann, H, Krude, H, Vollmert, C, Wichmann, H-E, Illig, T, Sørensen, TIA, Astrup, A, Larsen, LH, Pedersen, O, Eberlé, D, Clément, K, Blundell, J, Wabitsch, M, Schäfer, H, Platzer, M, Hinney, A & Hebebrand, J 2005, 'Mutation analysis of the MCHR1 gene in human obesity', European Journal of Endocrinology, vol. 152, no. 6, pp. 851-62. https://doi.org/10.1530/eje.1.01917

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title = "Mutation analysis of the MCHR1 gene in human obesity",

abstract = "The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.",

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AU - Wermter, Anne-Kathrin

AU - Reichwald, Kathrin

AU - Büch, Thomas

AU - Geller, Frank

AU - Platzer, Cornelia

AU - Huse, Klaus

AU - Hess, Claudia

AU - Remschmidt, Helmut

AU - Gudermann, Thomas

AU - Preibisch, Gerald

AU - Siegfried, Wolfgang

AU - Goldschmidt, Hans-Peter

AU - Li, Wei-Dong

AU - Price, R Arlen

AU - Biebermann, Heike

AU - Krude, Heiko

AU - Vollmert, Caren

AU - Wichmann, H-Erich

AU - Illig, Thomas

AU - Sørensen, Thorkild I A

AU - Astrup, Arne

AU - Larsen, Lesli Hingstrup

AU - Pedersen, Oluf

AU - Eberlé, Delphine

AU - Clément, Karine

AU - Blundell, John

AU - Wabitsch, Martin

AU - Schäfer, Helmut

AU - Platzer, Matthias

AU - Hinney, Anke

AU - Hebebrand, Johannes

PY - 2005

Y1 - 2005

N2 - The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.

AB - The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. We analysed the human MCH receptor 1 gene (MCHR1) with respect to human obesity.

KW - Adolescent

KW - Adult

KW - Animals

KW - COS Cells

KW - Cercopithecus aethiops

KW - Cyclic AMP

KW - DNA

KW - Female

KW - Humans

KW - Inositol Phosphates

KW - Male

KW - Mitogen-Activated Protein Kinases

KW - Obesity

KW - Polymerase Chain Reaction

KW - Polymorphism, Restriction Fragment Length

KW - Polymorphism, Single Nucleotide

KW - Polymorphism, Single-Stranded Conformational

KW - Receptors, Pituitary Hormone

KW - Sequence Analysis, DNA

U2 - 10.1530/eje.1.01917

DO - 10.1530/eje.1.01917

M3 - Journal article

C2 - 15941924

SN - 0804-4643

VL - 152

SP - 851

EP - 862

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

IS - 6

ER -

Mutation analysis of the MCHR1 gene in human obesity

Abstract

Keywords

UN SDGs

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