Modulating gene function with peptide nucleic acids (PNA)

Peter E. Nielsen; Stanley T. Crooke

Modulating gene function with peptide nucleic acids (PNA)

Institut for Cellulær og Molekylær Medicin

Abstract

A review on peptide nucleic acid (PNA) oligomers as modulators of gene expression ranging from gene silencing at the mRNAor the dsDNA (antigene) level, and redirection of mRNA splicing to gene activation through transcription bubble mimicking. PNA chem., anti-infective agents, cellular delivery, and in vivo bioavailability of PNA are briefly discussed. [on SciFinder (R)]

Originalsprog	Dansk
Titel	Antisense Drug Technology
Antal sider	11
Vol/bind	18
Forlag	Taylor & Francis
Publikationsdato	2008
Udgave	2nd
Sider	507-518
Status	Udgivet - 2008

Citationsformater

@inbook{b9cbf2f0ed1511ddbf70000ea68e967b,

title = "Modulating gene function with peptide nucleic acids (PNA)",

abstract = "A review on peptide nucleic acid (PNA) oligomers as modulators of gene expression ranging from gene silencing at the mRNAor the dsDNA (antigene) level, and redirection of mRNA splicing to gene activation through transcription bubble mimicking. PNA chem., anti-infective agents, cellular delivery, and in vivo bioavailability of PNA are briefly discussed. [on SciFinder (R)]",

author = "Nielsen, {Peter E.} and Crooke, {Stanley T.}",

note = "Copyright (C) 2007 ACS on SciFinder (R))Database:CAPLUSAccession Number:AN 2007:1031467Chemical Abstracts Number(CAN):Section Code:1Section Title:PharmacologyCA Section Cross-references:Document Type:Conference; General ReviewCODEN:69JTSLLanguage:written in EnglishIndex Terms:Index Terms(2):END_RECORD",

year = "2008",

language = "Dansk",

volume = "18",

pages = "507--518",

booktitle = "Antisense Drug Technology",

publisher = "Taylor & Francis",

address = "USA",

edition = "2nd",

}

TY - CHAP

T1 - Modulating gene function with peptide nucleic acids (PNA)

AU - Nielsen, Peter E.

AU - Crooke, Stanley T.

N1 - Copyright (C) 2007 ACS on SciFinder (R))Database:CAPLUSAccession Number:AN 2007:1031467Chemical Abstracts Number(CAN):Section Code:1Section Title:PharmacologyCA Section Cross-references:Document Type:Conference; General ReviewCODEN:69JTSLLanguage:written in EnglishIndex Terms:Index Terms(2):END_RECORD

PY - 2008

Y1 - 2008

N2 - A review on peptide nucleic acid (PNA) oligomers as modulators of gene expression ranging from gene silencing at the mRNAor the dsDNA (antigene) level, and redirection of mRNA splicing to gene activation through transcription bubble mimicking. PNA chem., anti-infective agents, cellular delivery, and in vivo bioavailability of PNA are briefly discussed. [on SciFinder (R)]

AB - A review on peptide nucleic acid (PNA) oligomers as modulators of gene expression ranging from gene silencing at the mRNAor the dsDNA (antigene) level, and redirection of mRNA splicing to gene activation through transcription bubble mimicking. PNA chem., anti-infective agents, cellular delivery, and in vivo bioavailability of PNA are briefly discussed. [on SciFinder (R)]

M3 - Bidrag til bog/antologi

VL - 18

SP - 507

EP - 518

BT - Antisense Drug Technology

PB - Taylor & Francis

ER -