Microwave-assisted solid-phase Ugi four-component condensations

Andreas M L Hoel; John Nielsen

doi:10.1016/S0040-4039(99)00616-4

Microwave-assisted solid-phase Ugi four-component condensations

Andreas M L Hoel, John Nielsen^*

^*Corresponding author af dette arbejde

91 Citationer (Scopus)

Abstract

An 18-member library was constructed from 2 isocyanides, 3 aldehydes and 3 carboxylic acids via microwave-assisted solid-phase Ugi reactions on TentaGel S RAM. Products of high purity were obtained in moderate to excellent yields after reaction times of 5 minutes or less (irradiation at 60W).

Originalsprog	Engelsk
Tidsskrift	Tetrahedron Letters
Vol/bind	40
Udgave nummer	20
Sider (fra-til)	3941-3944
Antal sider	4
ISSN	0040-4039
DOI	https://doi.org/10.1016/S0040-4039(99)00616-4
Status	Udgivet - 14 maj 1999

Adgang til dokumentet

10.1016/S0040-4039(99)00616-4

http://www.scopus.com/inward/record.url?scp=0033553530&partnerID=8YFLogxK

Citationsformater

@article{c2a0e8ef36784eb68dd92806f48554d8,

title = "Microwave-assisted solid-phase Ugi four-component condensations",

abstract = "An 18-member library was constructed from 2 isocyanides, 3 aldehydes and 3 carboxylic acids via microwave-assisted solid-phase Ugi reactions on TentaGel S RAM. Products of high purity were obtained in moderate to excellent yields after reaction times of 5 minutes or less (irradiation at 60W).",

keywords = "Combinatorial chemistry, Microwave heating, Solid-Phase synthesis, Ugi-Passerini reactions",

author = "Hoel, {Andreas M L} and John Nielsen",

year = "1999",

month = may,

day = "14",

doi = "10.1016/S0040-4039(99)00616-4",

language = "English",

volume = "40",

pages = "3941--3944",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Pergamon Press",

number = "20",

}

TY - JOUR

T1 - Microwave-assisted solid-phase Ugi four-component condensations

AU - Hoel, Andreas M L

AU - Nielsen, John

PY - 1999/5/14

Y1 - 1999/5/14

N2 - An 18-member library was constructed from 2 isocyanides, 3 aldehydes and 3 carboxylic acids via microwave-assisted solid-phase Ugi reactions on TentaGel S RAM. Products of high purity were obtained in moderate to excellent yields after reaction times of 5 minutes or less (irradiation at 60W).

AB - An 18-member library was constructed from 2 isocyanides, 3 aldehydes and 3 carboxylic acids via microwave-assisted solid-phase Ugi reactions on TentaGel S RAM. Products of high purity were obtained in moderate to excellent yields after reaction times of 5 minutes or less (irradiation at 60W).

KW - Combinatorial chemistry

KW - Microwave heating

KW - Solid-Phase synthesis

KW - Ugi-Passerini reactions

U2 - 10.1016/S0040-4039(99)00616-4

DO - 10.1016/S0040-4039(99)00616-4

M3 - Journal article

AN - SCOPUS:0033553530

SN - 0040-4039

VL - 40

SP - 3941

EP - 3944

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 20

ER -

Microwave-assisted solid-phase Ugi four-component condensations

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater