Microbial glycoproteomics

TY - JOUR

T1 - Microbial glycoproteomics

AU - Halim, Adnan

AU - Anonsen, Jan Haug

N1 - Copyright © 2017 Elsevier Ltd. All rights reserved.

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Mass spectrometry-based "-omics" technologies are important tools for global and detailed mapping of post-translational modifications. Protein glycosylation is an abundant and important post translational modification widespread throughout all domains of life. Characterization of glycoproteins, including identification of glycan structure and components, their attachment sites and protein carriers, remains challenging. However, recent advances in glycoproteomics, a subbranch that studies and categorizes protein glycosylations, have greatly expanded the known protein glycosylation space and research in this area is rapidly accelerating. Here, we review recent developments in glycoproteomic technologies with a special focus on microbial protein glycosylation.

AB - Mass spectrometry-based "-omics" technologies are important tools for global and detailed mapping of post-translational modifications. Protein glycosylation is an abundant and important post translational modification widespread throughout all domains of life. Characterization of glycoproteins, including identification of glycan structure and components, their attachment sites and protein carriers, remains challenging. However, recent advances in glycoproteomics, a subbranch that studies and categorizes protein glycosylations, have greatly expanded the known protein glycosylation space and research in this area is rapidly accelerating. Here, we review recent developments in glycoproteomic technologies with a special focus on microbial protein glycosylation.

U2 - 10.1016/j.sbi.2017.03.005

DO - 10.1016/j.sbi.2017.03.005

M3 - Journal article

C2 - 28365498

SN - 0959-440X

VL - 44

SP - 143

EP - 150

JO - Current Opinion in Structural Biology

JF - Current Opinion in Structural Biology

ER -