Metabolism of oral trefoil factor 2 (TFF2) and the effect of oral and parenteral TFF2 on gastric and duodenal ulcer healing in the rat

Steen Seier Poulsen, J Thulesen, L Christensen, E Nexo, L Thim

67 Citationer (Scopus)

Abstract

Trefoil factors (TFFs) are peptides produced by mucus-secreting cells in the gastrointestinal tract. A functional association between these peptides and mucus, leading to stabilisation of the viscoelastic gel overlying the epithelia, has been suggested. Both oral and parenteral administration of the peptides increase the resistance of the gastric mucosa.
OriginalsprogEngelsk
TidsskriftGut
Vol/bind45
Udgave nummer4
Sider (fra-til)516-22
Antal sider7
ISSN0017-5749
StatusUdgivet - 1 okt. 1999

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