Magnetic resonance imaging with liver-specific contrast agent in primary amyloidosis and intrahepatic cholestasis

J. M. Møller; E. Santoni-Rugiu; E. Chabanova; V. Løgager; A. B. Hansen; H. S. Thomsen

doi:10.1080/02841850601128959

Magnetic resonance imaging with liver-specific contrast agent in primary amyloidosis and intrahepatic cholestasis

J. M. Møller^*, E. Santoni-Rugiu, E. Chabanova, V. Løgager, A. B. Hansen, H. S. Thomsen

^*Corresponding author af dette arbejde

7 Citationer (Scopus)

Abstract

Magnetic resonance imaging (MRI) findings in hepatic amyloidosis are not well defined. Here, we report on a patient with renal failure caused by primary amyloidosis (AL type) who developed jaundice. Ultrasound and computed tomography were normal except for some ascites. MRI with oral manganese-containing contrast agent revealed several focal areas without contrast uptake in the hepatocytes and no bile secretion after 8 hours. No extrahepatic bile obstructions were found. Liver biopsy showed severe intraportal, vascular, and parenchymal amyloidosis causing severe cholestasis and atrophy of hepatocytes.

Originalsprog	Engelsk
Tidsskrift	Acta Radiologica
Vol/bind	48
Udgave nummer	2
Sider (fra-til)	145-149
Antal sider	5
ISSN	0284-1851
DOI	https://doi.org/10.1080/02841850601128959
Status	Udgivet - 16 mar. 2007

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abstract = "Magnetic resonance imaging (MRI) findings in hepatic amyloidosis are not well defined. Here, we report on a patient with renal failure caused by primary amyloidosis (AL type) who developed jaundice. Ultrasound and computed tomography were normal except for some ascites. MRI with oral manganese-containing contrast agent revealed several focal areas without contrast uptake in the hepatocytes and no bile secretion after 8 hours. No extrahepatic bile obstructions were found. Liver biopsy showed severe intraportal, vascular, and parenchymal amyloidosis causing severe cholestasis and atrophy of hepatocytes.",

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AU - Møller, J. M.

AU - Santoni-Rugiu, E.

AU - Chabanova, E.

AU - Løgager, V.

AU - Hansen, A. B.

AU - Thomsen, H. S.

PY - 2007/3/16

Y1 - 2007/3/16

N2 - Magnetic resonance imaging (MRI) findings in hepatic amyloidosis are not well defined. Here, we report on a patient with renal failure caused by primary amyloidosis (AL type) who developed jaundice. Ultrasound and computed tomography were normal except for some ascites. MRI with oral manganese-containing contrast agent revealed several focal areas without contrast uptake in the hepatocytes and no bile secretion after 8 hours. No extrahepatic bile obstructions were found. Liver biopsy showed severe intraportal, vascular, and parenchymal amyloidosis causing severe cholestasis and atrophy of hepatocytes.

AB - Magnetic resonance imaging (MRI) findings in hepatic amyloidosis are not well defined. Here, we report on a patient with renal failure caused by primary amyloidosis (AL type) who developed jaundice. Ultrasound and computed tomography were normal except for some ascites. MRI with oral manganese-containing contrast agent revealed several focal areas without contrast uptake in the hepatocytes and no bile secretion after 8 hours. No extrahepatic bile obstructions were found. Liver biopsy showed severe intraportal, vascular, and parenchymal amyloidosis causing severe cholestasis and atrophy of hepatocytes.

KW - Abdomen

KW - Bile duct

KW - Liver

KW - MR imaging

KW - Oral contrast agent

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M3 - Journal article

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SN - 0365-5954

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JO - Acta Radiologica - Series Diagnosis

JF - Acta Radiologica - Series Diagnosis

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Magnetic resonance imaging with liver-specific contrast agent in primary amyloidosis and intrahepatic cholestasis

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