Liver failure in neonatal children is a diagnostic challenge

TY - JOUR

T1 - Liver failure in neonatal children is a diagnostic challenge

AU - Smedegaard, Heidi

AU - Christensen, Vibeke Brix

AU - Dziegiel, Morten Hanefeld

AU - Jørgensen, Marianne Hørby

PY - 2017/3/27

Y1 - 2017/3/27

N2 - This case report presents a newborn boy with hypoglycaemia, anaemia, jaundice and severe coagulopathy during the first day of his life, imitating sepsis and disseminated intravascular coagulation. One week after the birth he was diagnosed with acute liver failure due to gestational alloimmune liver disease (GALD). Despite the fact that GALD is rare, it must be suspected in all unexplained stillborn children and infants with severe liver disease. If diagnosed, it is possible to prevent death and severe liver failure in future newborns by treating the affected women with immunoglobulin during pregnancy.

AB - This case report presents a newborn boy with hypoglycaemia, anaemia, jaundice and severe coagulopathy during the first day of his life, imitating sepsis and disseminated intravascular coagulation. One week after the birth he was diagnosed with acute liver failure due to gestational alloimmune liver disease (GALD). Despite the fact that GALD is rare, it must be suspected in all unexplained stillborn children and infants with severe liver disease. If diagnosed, it is possible to prevent death and severe liver failure in future newborns by treating the affected women with immunoglobulin during pregnancy.

UR - http://www.scopus.com/inward/record.url?scp=85060195619&partnerID=8YFLogxK

M3 - Journal article

C2 - 28397655

AN - SCOPUS:85060195619

SN - 0041-5782

VL - 179

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 13

ER -