@article{530b26e21c4f4bb89a2466da1d9bd1df,
title = "Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion",
abstract = "Polymorphisms of the butyrylcholinesterase gene (BCHE) are reported to associate with Alzheimer's disease and a recent study found a significant association of the BCHE K variant (G1615A/Ala539Thr) with Type 2 diabetes. The objectives of our study were to examine whether the BCHE K variant is associated with Type 2 diabetes or estimates of pancreatic beta cell function in large-scale populations of glucose-tolerant Caucasians.",
keywords = "Amino Acid Substitution, Base Sequence, Blood Glucose, Butyrylcholinesterase, DNA Primers, Diabetes Mellitus, Type 2, Gene Frequency, Genetic Variation, Genotype, Humans, Insulin, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Polymorphism, Single Nucleotide, Reference Values",
author = "A Johansen and Nielsen, {E-M D} and G Andersen and Hamid, {Y H} and Jensen, {D P} and C Gl{\"u}mer and T Drivsholm and K Borch-Johnsen and T J{\o}rgensen and T Hansen and O Pedersen",
year = "2004",
month = aug,
day = "1",
doi = "10.1007/s00125-004-1459-7",
language = "English",
volume = "47",
pages = "1437--41",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "8",
}
