Intrauterine growth restriction reduces intestinal structure and modifies the response to colostrum in preterm and term piglets

R. D'Inca, L. Che, Thomas Thymann, Per Torp Sangild, I. Le Huerou-Luron

    26 Citationer (Scopus)

    Abstract

    We investigated some consequences of intrauterine growth restriction (IUGR) on weight and structural and functional parameters of the intestine at birth and after 2. days of colostrum feeding. IUGR altered intestinal morphology, leading to a longer and thinner small intestine in piglets born both preterm and at full term, together with reduced villous size in term IUGR piglets. Preterm IUGR piglets displayed an improved ability to adapt to colostrum intake by rapid intestinal catch-up growth, relative to other groups of pigs. In contrast, intestinal nutrient absorption surface was impaired by IUGR during the first days of life in term piglets. The postnatal effects of IUGR may have long term consequences for developing piglets, and these effects may depend on gestational age at birth, preterm or term.

    OriginalsprogEngelsk
    TidsskriftLivestock Science
    Vol/bind133
    Udgave nummer1-3
    Sider (fra-til)20-22
    Antal sider3
    ISSN1871-1413
    DOI
    StatusUdgivet - sep. 2010

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