@article{317c98dba3ed4cad907c8448b6fe4fba,
title = "Interleukin-4 and 13 induce the expression and release of monocyte chemoattractant protein 1, interleukin-6 and stem cell factor from human detrusor smooth muscle cells: synergy with interleukin-1beta and tumor necrosis factor-alpha",
abstract = "Interstitial cystitis is characterized by an increased number of activated MCs in the detrusor muscle. However, to our knowledge the factors that influence the anatomical relationship between MCs and HDSMCs are unknown. MCP-1, IL-6 and SCF have a critical role in the regulation of MC development, signaling and function. We investigated whether HDSMCs are capable of expressing and releasing MCP-1, IL-6 and SCF in response to IL-4, IL-13, IL-1beta and tumor necrosis factor-alpha.",
keywords = "Cells, Cultured, Chemokine CCL2, Humans, Interleukin-1, Interleukin-13, Interleukin-4, Interleukin-6, Muscle, Smooth, Stem Cell Factor, Tumor Necrosis Factor-alpha",
author = "Kirsten Bouchelouche and Lars Andresen and Susana Alvarez and Jorgen Nordling and Nielsen, {Ole Haagen} and Pierre Bouchelouche",
year = "2006",
doi = "10.1016/S0022-5347(05)00167-9",
language = "English",
volume = "175",
pages = "760--5",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier",
number = "2",
}