TY - JOUR
T1 - Initial experience with EUS-guided microbiopsy forceps in diagnosing pancreatic cystic lesions
T2 - A multicenter feasibility study (with video)
AU - Kovacevic, Bojan
AU - Karstensen, John Gásdal
AU - Havre, Roald Flesland
AU - Pham, Khanh Do Cong
AU - Giovannini, Marc
AU - Dabizzi, Emanuele
AU - Arcidiacono, Paolo
AU - Santo, Erwin
AU - Sequeiros, Enrique Vazquez
AU - Klausen, Pia
AU - Rift, Charlotte Vestrup
AU - Hasselby, Jane Preuss
AU - Toxværd, Anders
AU - Kalaitzakis, Evangelos
AU - Hansen, Carsten Palnæs
AU - Vilmann, Peter
PY - 2018
Y1 - 2018
N2 - Background and Objectives: Cystic lesions of the pancreas represent a diagnostic dilemma. Recently, a through-the-needle microbiopsy forceps has become available, enabling procurement of EUS-guided histological specimens from the pancreatic cyst wall. The aim of this study was to evaluate the use of this novel instrument in a multicenter clinical setting. Patients and Methods: Patients referred for EUS evaluation of pancreatic cysts and attempted EUS-guided microbiopsy was included retrospectively from six international tertiary centers. Patient’s demographics, EUS findings, technical and clinical success, and histopathological results were recorded. Results: A total of 28 patients were identified. We report a technical success rate of 85.7% (n = 24). Biopsies were generally of good quality and contributed to the diagnosis in 20 patients (clinical success of 71.4%). Three adverse events were recorded (10.7%). Conclusions: The use of the microbiopsy forceps is feasible with acceptable rates of technical and clinical success. Prospective studies are warranted to determine the diagnostic potential compared to the other modalities. However, the results from this preliminary study are promising.
AB - Background and Objectives: Cystic lesions of the pancreas represent a diagnostic dilemma. Recently, a through-the-needle microbiopsy forceps has become available, enabling procurement of EUS-guided histological specimens from the pancreatic cyst wall. The aim of this study was to evaluate the use of this novel instrument in a multicenter clinical setting. Patients and Methods: Patients referred for EUS evaluation of pancreatic cysts and attempted EUS-guided microbiopsy was included retrospectively from six international tertiary centers. Patient’s demographics, EUS findings, technical and clinical success, and histopathological results were recorded. Results: A total of 28 patients were identified. We report a technical success rate of 85.7% (n = 24). Biopsies were generally of good quality and contributed to the diagnosis in 20 patients (clinical success of 71.4%). Three adverse events were recorded (10.7%). Conclusions: The use of the microbiopsy forceps is feasible with acceptable rates of technical and clinical success. Prospective studies are warranted to determine the diagnostic potential compared to the other modalities. However, the results from this preliminary study are promising.
KW - EUS-FNA
KW - IPMN
KW - Microbiopsy forceps
KW - Moray
KW - Pancreatic cancer
KW - Pancreatic cysts
U2 - 10.4103/eus.eus_16_18
DO - 10.4103/eus.eus_16_18
M3 - Journal article
C2 - 30168479
AN - SCOPUS:85057625812
SN - 2303-9027
VL - 7
SP - 383
EP - 388
JO - Endoscopic Ultrasound
JF - Endoscopic Ultrasound
IS - 6
ER -
