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In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study
Ina Petry,
Korbinian Löbmann
,
Holger Grohganz
,
Thomas Rades
, Claudia S. Leopold
*
*
Corresponding author af dette arbejde
7
Citationer (Scopus)
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Alfabetisk
Medicin og biovidenskab
Proof of Concept Study
90%
Furosemide
83%
Immersion
79%
Indomethacin
71%
Arginine
66%
Eudragit-E
38%
Tablets
28%
Hydrolysis
19%
methylmethacrylate-methacrylic acid copolymer
14%
Basic Amino Acids
14%
Water
13%
Naproxen
13%
Humidity
11%
Fourier Transform Infrared Spectroscopy
11%
Citric Acid
11%
Spectrum Analysis
10%
Polymers
9%
Molecular Weight
8%
Pharmaceutical Preparations
8%
Temperature
7%
Kemiske forbindelser
Furosemide
100%
Arginine
72%
Amorphization
35%
Hydrolysis
17%
Drug
15%
Citric Acid
13%
Humidity
12%
Water Soluble
11%
Time
10%
Coating Agent
8%
Fourier Transform Infrared Spectroscopy
8%
Weight
7%
Mixture
6%
Acid
5%