Grafted biomembranes containing membrane proteins – the case of the leucine transporter

Vivien Jagalski; Robert D. Barker; Mikkel Boas Thygesen; Kamil Gotfryd; Mie Barthold Krüger; Lei Shi; Selma Maric; Nicolas Emile Bovet; Martine Moulin; Michael Haertlein; Thomas Günther-Pomorski; Claus Juul Løland; Marite Cardenas Gomez

doi:10.1039/c5sm01490e

Grafted biomembranes containing membrane proteins – the case of the leucine transporter

Vivien Jagalski, Robert D. Barker, Mikkel Boas Thygesen, Kamil Gotfryd, Mie Barthold Krüger, Lei Shi, Selma Maric, Nicolas Emile Bovet, Martine Moulin, Michael Haertlein, Thomas Günther-Pomorski, Claus Juul Løland, Marite Cardenas Gomez

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Abstract

Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations.

Originalsprog	Engelsk
Tidsskrift	Soft Matter
Vol/bind	11
Udgave nummer	39
Sider (fra-til)	7707-7711
Antal sider	5
ISSN	1744-683X
DOI	https://doi.org/10.1039/c5sm01490e
Status	Udgivet - 19 aug. 2015

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10.1039/c5sm01490eLicens: CC BY

Jagalski_2015_Grafted_biomembranes_containingForlagets udgivne version, 1,95 MBLicens: CC BY

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abstract = "Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations.",

author = "Vivien Jagalski and Barker, {Robert D.} and Thygesen, {Mikkel Boas} and Kamil Gotfryd and Kr{\"u}ger, {Mie Barthold} and Lei Shi and Selma Maric and Bovet, {Nicolas Emile} and Martine Moulin and Michael Haertlein and Thomas G{\"u}nther-Pomorski and L{\o}land, {Claus Juul} and {Cardenas Gomez}, Marite",

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doi = "10.1039/c5sm01490e",

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T1 - Grafted biomembranes containing membrane proteins – the case of the leucine transporter

AU - Jagalski, Vivien

AU - Barker, Robert D.

AU - Thygesen, Mikkel Boas

AU - Gotfryd, Kamil

AU - Krüger, Mie Barthold

AU - Shi, Lei

AU - Maric, Selma

AU - Bovet, Nicolas Emile

AU - Moulin, Martine

AU - Haertlein, Michael

AU - Günther-Pomorski, Thomas

AU - Løland, Claus Juul

AU - Cardenas Gomez, Marite

PY - 2015/8/19

Y1 - 2015/8/19

N2 - Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations.

AB - Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations.

U2 - 10.1039/c5sm01490e

DO - 10.1039/c5sm01490e

M3 - Journal article

C2 - 26325086

SN - 1744-683X

VL - 11

SP - 7707

EP - 7711

JO - Soft Matter

JF - Soft Matter

IS - 39

ER -

Grafted biomembranes containing membrane proteins – the case of the leucine transporter

Abstract

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