@article{06d76b70e4b811deba73000ea68e967b,
title = "Graft-derived anti-HPA-2b production after allogeneic bone-marrow transplantation",
abstract = "We report on a male who received a bone-marrow allograft from his HLA identical sister for acute myelogenous leukaemia. After transplantation, the patient suffered from refractoriness to the transfusions of HLA-matched platelets and a strong platelet-specific antibody, anti-HPA-2b, of IgG1 subclass was demonstrated in the patient's serum. In the serum of the bone-marrow donor a weak IgG1 anti-HPA-2b was demonstrated. IgG allotyping of the patient and donor showed identical results. We could not determine the origin of the anti-HPA-2b, although we hypothesize that the anti-HPA-2b was produced by immunocompetent donor lymphocytes infused with the suspension of bone-marrow cells.",
author = "E Taaning and N Jacobsen and N Morling",
note = "Keywords: Antigens, Human Platelet; Blood Platelets; Bone Marrow Transplantation; Humans; Immunoglobulin G; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Count; Platelet Transfusion; Transplantation, Homologous",
year = "1994",
language = "English",
volume = "86",
pages = "651--3",
journal = "British Journal of Haematology, Supplement",
issn = "0963-1860",
publisher = "Wiley-Blackwell",
number = "3",
}