Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

Pil Seok Chae; Rohini R Rana; Kamil Gotfryd; Søren G F Rasmussen; Andrew C Kruse; Kyung Ho Cho; Stefano Capaldi; Emil Carlsson; Brian Kobilka; Claus J Loland; Ulrik Gether; Surajit Banerjee; Bernadette Byrne; John K Lee; Samuel H Gellman

doi:10.1039/c2cc36844g

Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

Pil Seok Chae, Rohini R Rana, Kamil Gotfryd, Søren G F Rasmussen, Andrew C Kruse, Kyung Ho Cho, Stefano Capaldi, Emil Carlsson, Brian Kobilka, Claus J Loland, Ulrik Gether, Surajit Banerjee, Bernadette Byrne, John K Lee, Samuel H Gellman

Neuropharm and Genetics

61 Citationer (Scopus)

Abstract

The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

Originalsprog	Engelsk
Tidsskrift	Chemical communications (Cambridge, England)
Vol/bind	49
Udgave nummer	23
Sider (fra-til)	2287-9
Antal sider	3
ISSN	1359-7345
DOI	https://doi.org/10.1039/c2cc36844g
Status	Udgivet - 21 feb. 2013

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10.1039/c2cc36844g

Citationsformater

Chae, P. S., Rana, R. R., Gotfryd, K., Rasmussen, S. G. F., Kruse, A. C., Cho, K. H., Capaldi, S., Carlsson, E., Kobilka, B., Loland, C. J., Gether, U., Banerjee, S., Byrne, B., Lee, J. K., & Gellman, S. H. (2013). Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study. Chemical communications (Cambridge, England), 49(23), 2287-9. https://doi.org/10.1039/c2cc36844g

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author = "Chae, {Pil Seok} and Rana, {Rohini R} and Kamil Gotfryd and Rasmussen, {S{\o}ren G F} and Kruse, {Andrew C} and Cho, {Kyung Ho} and Stefano Capaldi and Emil Carlsson and Brian Kobilka and Loland, {Claus J} and Ulrik Gether and Surajit Banerjee and Bernadette Byrne and Lee, {John K} and Gellman, {Samuel H}",

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day = "21",

doi = "10.1039/c2cc36844g",

language = "English",

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T1 - Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

AU - Chae, Pil Seok

AU - Rana, Rohini R

AU - Gotfryd, Kamil

AU - Rasmussen, Søren G F

AU - Kruse, Andrew C

AU - Cho, Kyung Ho

AU - Capaldi, Stefano

AU - Carlsson, Emil

AU - Kobilka, Brian

AU - Loland, Claus J

AU - Gether, Ulrik

AU - Banerjee, Surajit

AU - Byrne, Bernadette

AU - Lee, John K

AU - Gellman, Samuel H

PY - 2013/2/21

Y1 - 2013/2/21

N2 - The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

AB - The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

U2 - 10.1039/c2cc36844g

DO - 10.1039/c2cc36844g

M3 - Journal article

C2 - 23165475

SN - 1359-7345

VL - 49

SP - 2287

EP - 2289

JO - Chemical communications (Cambridge, England)

JF - Chemical communications (Cambridge, England)

IS - 23

ER -

Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

Abstract

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