Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype

Sofia Inez Iqbal Kring, Lesli Hingstrup Larsen, Claus Holst, Søren Toubro, Torben Hansen, Arne Astrup, Oluf Pedersen, Thorkild I A Sørensen

35 Citationer (Scopus)

Abstract

In previous studies of associations of variants in the genes UCP2, UCP3, PPARG2, CART, GRL, MC4R, MKKS, SHP, GHRL, and MCHR1 with obesity, we have used a case-control approach with cases defined by a threshold for BMI. In the present study, we assess the association of seven abdominal, peripheral, and overall obesity phenotypes, which were analyzed quantitatively, and thirteen candidate gene polymorphisms in these ten genes in the same cohort.
OriginalsprogEngelsk
TidsskriftObesity Facts
Vol/bind1
Udgave nummer3
Sider (fra-til)138-145
Antal sider8
ISSN1662-4025
DOI
StatusUdgivet - 2008

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