Fiskelugt--det kunne vaere trimethylaminuri

Line Klingen Haugaard; Allan Meldgaard Lund; Poula Patursson; Ernst Christensen

Fiskelugt--det kunne vaere trimethylaminuri

Line Klingen Haugaard, Allan Meldgaard Lund, Poula Patursson, Ernst Christensen

Institut for Klinisk Medicin

Abstract

We present a case with a ten-year-old girl with trimethylaminuria (TMAU). Primary TMAU is caused by a deficiency of flavin monooxygenase 3 (FMO3) due to mutations in the FMO3-gene. Patients suffering from TMAU show an impaired enzymatic oxidation of fish-smelling trimethylamine, and their excretion of this amine in body fluids produces an unpleasant body odour. TMAU is also seen secondary to e.g. liver diseases. It remains unknown if TMAU causes other problems than malodour, and today social and psychological problems are considered the most important consequence. Treatment includes a low-choline diet and antibiotics.

Bidragets oversatte titel	[Fish odour--could be a sign of trimethylaminuria]
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	172
Udgave nummer	47
Sider (fra-til)	3268-9
Antal sider	2
ISSN	0041-5782
Status	Udgivet - 22 nov. 2010

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http://ugeskriftet.dk/videnskab/fiskelugt-det-kunne-vaere-trimethylaminuri

Citationsformater

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abstract = "We present a case with a ten-year-old girl with trimethylaminuria (TMAU). Primary TMAU is caused by a deficiency of flavin monooxygenase 3 (FMO3) due to mutations in the FMO3-gene. Patients suffering from TMAU show an impaired enzymatic oxidation of fish-smelling trimethylamine, and their excretion of this amine in body fluids produces an unpleasant body odour. TMAU is also seen secondary to e.g. liver diseases. It remains unknown if TMAU causes other problems than malodour, and today social and psychological problems are considered the most important consequence. Treatment includes a low-choline diet and antibiotics.",

author = "Haugaard, {Line Klingen} and Lund, {Allan Meldgaard} and Poula Patursson and Ernst Christensen",

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day = "22",

language = "Dansk",

volume = "172",

pages = "3268--9",

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TY - JOUR

T1 - Fiskelugt--det kunne vaere trimethylaminuri

AU - Haugaard, Line Klingen

AU - Lund, Allan Meldgaard

AU - Patursson, Poula

AU - Christensen, Ernst

PY - 2010/11/22

Y1 - 2010/11/22

N2 - We present a case with a ten-year-old girl with trimethylaminuria (TMAU). Primary TMAU is caused by a deficiency of flavin monooxygenase 3 (FMO3) due to mutations in the FMO3-gene. Patients suffering from TMAU show an impaired enzymatic oxidation of fish-smelling trimethylamine, and their excretion of this amine in body fluids produces an unpleasant body odour. TMAU is also seen secondary to e.g. liver diseases. It remains unknown if TMAU causes other problems than malodour, and today social and psychological problems are considered the most important consequence. Treatment includes a low-choline diet and antibiotics.

AB - We present a case with a ten-year-old girl with trimethylaminuria (TMAU). Primary TMAU is caused by a deficiency of flavin monooxygenase 3 (FMO3) due to mutations in the FMO3-gene. Patients suffering from TMAU show an impaired enzymatic oxidation of fish-smelling trimethylamine, and their excretion of this amine in body fluids produces an unpleasant body odour. TMAU is also seen secondary to e.g. liver diseases. It remains unknown if TMAU causes other problems than malodour, and today social and psychological problems are considered the most important consequence. Treatment includes a low-choline diet and antibiotics.

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 172

SP - 3268

EP - 3269

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 47

ER -

Fiskelugt--det kunne vaere trimethylaminuri

Abstract

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