Fish oil-supplementation from 9 to 12 months of age affects infant attention in a free-play test and is related to change in blood pressure

TY - JOUR

T1 - Fish oil-supplementation from 9 to 12 months of age affects infant attention in a free-play test and is related to change in blood pressure

AU - Harbild, Helle Liliegren

AU - Harsløf, Laurine Bente Schram

AU - Christensen, J. H.

AU - Kannass, K. N.

AU - Lauritzen, Lotte

N1 - CURIS 2013 NEXS 242

PY - 2013/10

Y1 - 2013/10

N2 - Introduction: This intervention examined whether fish-oil-supplementation in late infancy modifies free-play test scores and if this is related to blood pressure (BP) and mean RR interval. Patients and methods: 83 Danish 9-month-old infants were randomized to ±fish oil (FO) (3.4±1.1. mL/d) for 3. months and 61 of these completed the free-play-test before and after the intervention. Results: Most of the free-play scores changed during the intervention, but the intervention affected only the number of looks away from the toy, which was increased in +FO and decreased in -FO (p=0.037). The increased numbers of looks away were associated with an increase in erythrocyte eicosapentaenoic acid (r=0.401, p=0.017, n=35) and were also associated with a decrease in systolic-BP (r=-0.511, p<0.001, n=52). Conclusions: The results indicate that n-3 fatty acid intake also in late infancy can influence brain development and that the cognitive and cardiovascular effects may be related.

AB - Introduction: This intervention examined whether fish-oil-supplementation in late infancy modifies free-play test scores and if this is related to blood pressure (BP) and mean RR interval. Patients and methods: 83 Danish 9-month-old infants were randomized to ±fish oil (FO) (3.4±1.1. mL/d) for 3. months and 61 of these completed the free-play-test before and after the intervention. Results: Most of the free-play scores changed during the intervention, but the intervention affected only the number of looks away from the toy, which was increased in +FO and decreased in -FO (p=0.037). The increased numbers of looks away were associated with an increase in erythrocyte eicosapentaenoic acid (r=0.401, p=0.017, n=35) and were also associated with a decrease in systolic-BP (r=-0.511, p<0.001, n=52). Conclusions: The results indicate that n-3 fatty acid intake also in late infancy can influence brain development and that the cognitive and cardiovascular effects may be related.

U2 - 10.1016/j.plefa.2013.08.007

DO - 10.1016/j.plefa.2013.08.007

M3 - Journal article

C2 - 24045099

SN - 0952-3278

VL - 89

SP - 327

EP - 333

JO - Prostaglandins, Leukotrienes & Essential Fatty Acids

JF - Prostaglandins, Leukotrienes & Essential Fatty Acids

IS - 5

ER -