TY - JOUR
T1 - Exposure to ultrafine particles and respiratory hospitalisations in five European cities
AU - Samoli, Evangelia
AU - Andersen, Zorana Jovanovic
AU - Katsouyanni, Klea
AU - Hennig, Frauke
AU - Kuhlbusch, Thomas A J
AU - Bellander, Tom
AU - Cattani, Giorgio
AU - Cyrys, Josef
AU - Forastiere, Francesco
AU - Jacquemin, Bénédicte
AU - Kulmala, Markku
AU - Lanki, Timo
AU - Loft, Steffen
AU - Massling, Andreas
AU - Tobias, Aurelio
AU - Stafoggia, Massimo
AU - UF&HEALTH Study group
N1 - Copyright ©ERS 2016.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Epidemiological evidence on the associations between exposure to ultrafine particles (UFP), with aerodynamic electrical mobility diameters <100 nm, and health is limited. We gathered data on UFP from five European cities within 2001-2011 to investigate associations between short-term changes in concentrations and respiratory hospitalisations.We applied city-specific Poisson regression models and combined city-specific estimates to obtain pooled estimates. We evaluated the sensitivity of our findings to co-pollutant adjustment and investigated effect modification patterns by period of the year, age at admission and specific diagnoses.Our results for the whole time period do not support an association between UFP and respiratory hospitalisations, although we found suggestive associations among those 0-14 years old. We nevertheless report consistent adverse effect estimates during the warm period of the year, statistically significant after lag 2 when an increase by 10 000 particles per cm(3) was associated with a 4.27% (95% CI 1.68-6.92%) increase in hospitalisations. These effect estimates were robust to particles' mass or gaseous pollutants adjustment.Considering that our findings during the warm period may reflect better exposure assessment and that the main source of non-soluble UFP in urban areas is traffic, our results call for improved regulation of traffic emissions.
AB - Epidemiological evidence on the associations between exposure to ultrafine particles (UFP), with aerodynamic electrical mobility diameters <100 nm, and health is limited. We gathered data on UFP from five European cities within 2001-2011 to investigate associations between short-term changes in concentrations and respiratory hospitalisations.We applied city-specific Poisson regression models and combined city-specific estimates to obtain pooled estimates. We evaluated the sensitivity of our findings to co-pollutant adjustment and investigated effect modification patterns by period of the year, age at admission and specific diagnoses.Our results for the whole time period do not support an association between UFP and respiratory hospitalisations, although we found suggestive associations among those 0-14 years old. We nevertheless report consistent adverse effect estimates during the warm period of the year, statistically significant after lag 2 when an increase by 10 000 particles per cm(3) was associated with a 4.27% (95% CI 1.68-6.92%) increase in hospitalisations. These effect estimates were robust to particles' mass or gaseous pollutants adjustment.Considering that our findings during the warm period may reflect better exposure assessment and that the main source of non-soluble UFP in urban areas is traffic, our results call for improved regulation of traffic emissions.
KW - Journal Article
U2 - 10.1183/13993003.02108-2015
DO - 10.1183/13993003.02108-2015
M3 - Journal article
C2 - 27338189
SN - 0903-1936
VL - 48
SP - 674
EP - 682
JO - European Respiratory Journal
JF - European Respiratory Journal
IS - 3
ER -
